In Vivo and in Vitro Anabolic Potential of Essential Amino Acids Following Resistance Exercise
NCT ID: NCT05754125
Last Updated: 2023-11-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
12 participants
INTERVENTIONAL
2023-01-21
2024-01-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
TRIPLE
Study Groups
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Di-Leucine supplement
Participants will consume a amino acid supplement containing Di-Leucine following resistance exercise and their whole body anabolism will be determined over the subsequent 6 hours
Di-Leucine Supplement
Participants will consume a amino acid supplement containing Di-Leucine following resistance exercise and their whole body anabolism will be determined over the subsequent 6 hours
BCAA Supplement
Participants will consume a amino acid supplement containing branched chain amino acids (BCAA) following resistance exercise and their whole body anabolism will be determined over the subsequent hours
BCAA Supplement
Participants will consume a amino acid supplement containing branched chain amino acids (BCAA) following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Collagen Supplement
Participants will consume a amino acid supplement containing collagen protein following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Collagen Supplement
Participants will consume a amino acid supplement containing Collagen protein following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Interventions
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Di-Leucine Supplement
Participants will consume a amino acid supplement containing Di-Leucine following resistance exercise and their whole body anabolism will be determined over the subsequent 6 hours
BCAA Supplement
Participants will consume a amino acid supplement containing branched chain amino acids (BCAA) following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Collagen Supplement
Participants will consume a amino acid supplement containing Collagen protein following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Inability to adhere to protocol guidelines (e.g., alcohol, habitual diet)
* Regular tobacco use
* Illicit drug use (e.g., growth hormone, testosterone, etc.)
* Diagnosed medical condition under the care of a physician (e.g. type 2 diabetes)
* Inability to abstain from supplements (e.g. protein, creatine, HMB, BCAA, phosphatidic acid, etc.) at least three weeks before the trial
* Individuals on any medications known to affect protein metabolism (e.g., corticosteroids, non-steroidal anti-inflammatories, or prescription-strength acne medications)
* Participants that are amenorrheic (females only)
* On medications that may interfere with protein metabolism (e.g. anti-inflammatory drugs, hormone therapy)
* Regular tobacco use (e.g. daily use of oral or inhaled tobacco)
* Illicit drug use (e.g. growth hormone, testosterone, etc.)
* Inability to comply with the study protocol as judged by the investigators
18 Years
35 Years
ALL
Yes
Sponsors
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University of Toronto
OTHER
Responsible Party
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Daniel Moore
Associate Professor
Locations
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Goldring Centre for High Performance Sport at the University of Toronto
Toronto, Ontario, Canada
Countries
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Other Identifiers
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DiEx
Identifier Type: -
Identifier Source: org_study_id
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