Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men

NCT ID: NCT06061315

Last Updated: 2025-04-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 80 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-09-15
• Study Completion Date: 2024-11-23

Brief Summary

The effect of resistance training with post-exercise Collagen peptides (CP) supplementation on lean body mass, maximal and explosive, isometric muscle strength as well as fat mass, resting metabolism, health parameters and compared to resistance training alone will be evaluated in a group of untrained overweight male (30-60 yrs) population in a randomized controlled trial (RCT).

Detailed Description

Participants will perform supervised resistance training involving (Leg press, pull down, chest press, back extension and abdominal crunches) 3 times a week for 12 weeks. Participants will consume either placebo or collagen peptides (in a double blinded study design) just following resistance training on training days (And approximately the same time of day on non-training days). Prior to, and following 12 weeks of exercise, participants will be tested in body composition, maximal and explosive, isometric muscle strength, resting metabolism, health parameters. Additionally, blood samples will be taken to ensure health and training eligibility and safety.

Participants are healthy untrained overweight males (30-60 yrs)

Conditions

Body Composition; Lean Body Mass; Muscle Strength; Muscle Power

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

Collagen peptide group

This group will consume 1 serving of Collagen peptides, which is produced and marketed ® by GELITA AG, Germany under the brand name BODYBALANC each day.

Group Type: EXPERIMENTAL

Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men

Intervention Type: DIETARY_SUPPLEMENT

The effects of collagen peptide consumption in combination with resistance training will be tested

Placebo group

This group will consume 1 serving of silicon dioxide (Sipernat 350, Evonik, Germany) each day. The product is absorbed in negligible amounts by the intestine and does therefore induce minor metabolic effects.

Group Type: PLACEBO_COMPARATOR

Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men

Intervention Type: DIETARY_SUPPLEMENT

The effects of placebo consumption in combination with resistance training will be tested

Interventions

Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men

The effects of collagen peptide consumption in combination with resistance training will be tested

Intervention Type: DIETARY_SUPPLEMENT

Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men

The effects of placebo consumption in combination with resistance training will be tested

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Male, between 30 and 60 years of age
• Fat mass >25 % as measured by bioelectrical impedance analysis
• Stable weight (±5 %) and eating behaviour within the last 3 months.
• Signed informed consent

Exclusion Criteria

• Regular physical activity >60 min / week
• Stabile or progressive diseases/conditions (including medication) contraindicating or disabling participation in intensive exercise training and/or with potential to affect training adaptation beyond normal variation. For example:
• Contraindications against physical stress corresponding guidelines of American College of Sports Medicine (ACSM)
• Subjective symptoms during exercise (e.g., unusual physical exhaustion, dyspnoea, nausea)
• Moderate to severe mobility limitation (i.e., due to rheumatic disease)
• Diagnosis of cancer within the last 5 years
• Diabetes mellitus I and II uncontrolled arterial hypertension (systolic blood pressure >155 for mmHg and/or diastolic blood pressure >94 mm Hg; mild hypertension under resting condition will be allowed but such participants will be recommended to consult their general practitioner).
• Conditions contraindicating the supplementation protocol.
• Contraindications against nutritional or ergogenic supplements
• Allergy/aversion against animal protein
• Liver or kidney diseases with a non-permission to ingest certain concentrations of protein.

• Minimum Eligible Age: 30 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

CRI Collagen Research Institute GmbH

UNKNOWN

Sponsor Role: collaborator

University of Southern Denmark

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

The Department of Sports Science and Clinical Biomechanics at University of Southern Denmark

Odense, , Denmark

Countries

Denmark

Other Identifiers

7260992052

Identifier Type: -

Identifier Source: org_study_id