Effects of Collagen Peptide Supplementation on Muscle and Tendon Damage and Function

NCT ID: NCT05425407

Last Updated: 2022-06-21

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 22 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-04-12
• Study Completion Date: 2021-06-30

Brief Summary

The aim of the study is to investigate the acute and short-term effects of collagen peptides (Collagen Peptan) on muscle and connective tissue during an eccentric overload training period. Currently, all studies investigating the effects of post-exercise collagen supplementation did this in the absence of whey proteins, which are part of the standard recommendations for post-exercise recovery. The investigators will therefore investigate whether the combined intake of whey proteins and collagen peptides ensures a better recovery of exercise performance and whether it can prevent or reduce symptoms of muscle and tendon overload during a three-week eccentric overload training period (n = 22).

Conditions

Exercise; Healthy Male Subjects

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: QUADRUPLE

Study Groups

Placebo

Only whey protein will be provided

Group Type: PLACEBO_COMPARATOR

whey protein

Intervention Type: DIETARY_SUPPLEMENT

Daily 45g of whey protein supplementation during a three week eccentric training period

Collagen

A mix of whey protein and collagen peptides will be provided

Group Type: EXPERIMENTAL

whey protein + collagen peptide

Intervention Type: DIETARY_SUPPLEMENT

Daily 15g of whey protein and 20g collagen peptide supplementation during a three week eccentric training period

Interventions

whey protein

Daily 45g of whey protein supplementation during a three week eccentric training period

Intervention Type: DIETARY_SUPPLEMENT

whey protein + collagen peptide

Daily 15g of whey protein and 20g collagen peptide supplementation during a three week eccentric training period

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Sports participation, including general fitness training, between 2 and 5 hours max per week
• Body mass index between 18.5 and 25

Exclusion Criteria

• Any kind of injury/pathology that is a contra-indication to perform high-intensity exercise - Intake of any medication or nutritional supplement that could impact muscle protein synthesis and/or exercise performance during the period of the study
• Intake of any whey protein, casein of branched-chain amino acid (BCAA) supplements from 1 month prior to the start of the study
• Blood donation within 3 months prior to the start of the study
• Smoking
• Current participation in another research trial
• Any other argument to believe that the subject is unlikely to successfully complete the full study

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Rousselot BVBA

INDUSTRY

Sponsor Role: collaborator

KU Leuven

OTHER

Sponsor Role: lead

Responsible Party

Peter Hespel

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Exercise Physiology Research Group

Leuven, Vlaams-Brabant, Belgium

Countries

Belgium

Other Identifiers

S64402

Identifier Type: -

Identifier Source: org_study_id