Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
22 participants
INTERVENTIONAL
2011-04-30
2013-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Immobilization and Leucine
Leucine
7.2 g of leucine during 2 weeks
Immobilization and Placebo
Placebo
7.2 g of alanine during 2 weeks
Interventions
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Leucine
7.2 g of leucine during 2 weeks
Placebo
7.2 g of alanine during 2 weeks
Eligibility Criteria
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Inclusion Criteria
* Physically active
* Must be able to swallow tablets
* Non-smokers
* Do not use nutritional supplements
Exclusion Criteria
18 Years
35 Years
MALE
Yes
Sponsors
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University of Sao Paulo
OTHER
Responsible Party
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Humberto Nicastro
PhD
Principal Investigators
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Humberto Nicastro, PhD Student
Role: PRINCIPAL_INVESTIGATOR
University of Sao Paulo
Locations
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University of São Paulo - School of Physical Education and Sports
São Paulo, São Paulo, Brazil
Countries
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References
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Zanchi NE, Nicastro H, Lancha AH Jr. Potential antiproteolytic effects of L-leucine: observations of in vitro and in vivo studies. Nutr Metab (Lond). 2008 Jul 17;5:20. doi: 10.1186/1743-7075-5-20.
Nicastro H, Artioli GG, Costa Ados S, Solis MY, da Luz CR, Blachier F, Lancha AH Jr. An overview of the therapeutic effects of leucine supplementation on skeletal muscle under atrophic conditions. Amino Acids. 2011 Feb;40(2):287-300. doi: 10.1007/s00726-010-0636-x. Epub 2010 Jun 1.
Other Identifiers
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2009/02896-6
Identifier Type: -
Identifier Source: org_study_id
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