Circuit Training and Retina

NCT ID: NCT05714813

Last Updated: 2023-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-09-30

Brief Summary

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The purpose of this research study is to see if high-speed weight training performed in a circuit (using one machine after another) can improve participant heart and brain function, strength, and power in older persons.

Detailed Description

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Conditions

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Cognitive Impairment, Progressive Cerebral Small Vessel Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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High-Speed Circuit Resistance Training Group

Participants in this group will receive high-speed circuit resistance training 3 times a week for 24 consecutive weeks for a total of 72 training sessions.

Group Type EXPERIMENTAL

High-Speed Circuit Resistance Training

Intervention Type BEHAVIORAL

Performance of 24 weeks of high-speed concentric and low-speed eccentric lift across three circuits on eleven pneumatic machines. Each training session will be in person and will last between 45 minutes and one hour.

Control Group

Participants in this arm will receive two lectures on fitness, diet, or cognition each month for 24 weeks for a total of 12 lectures.

Group Type OTHER

Lecture on Diet, Exercise and Cognition

Intervention Type BEHAVIORAL

Lectures on diet, exercise, and cognition. Lectures will be provided in person or online and will last approximately one hour.

Interventions

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High-Speed Circuit Resistance Training

Performance of 24 weeks of high-speed concentric and low-speed eccentric lift across three circuits on eleven pneumatic machines. Each training session will be in person and will last between 45 minutes and one hour.

Intervention Type BEHAVIORAL

Lecture on Diet, Exercise and Cognition

Lectures on diet, exercise, and cognition. Lectures will be provided in person or online and will last approximately one hour.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. 65-90 years of age;
2. Montreal Cognitive Assessment (MoCA) \> 23
3. no memory loss complaints

Exclusion Criteria

1. Uncontrolled cardiovascular or neuromuscular diseases that prevent participation in a training program;
2. Cerebrovascular disease;
3. Malignancy within the previous 5 years;
4. Documented HIV infection or other immunodeficiency syndrome;
5. Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, or other serious concomitant medical illness;
6. A history of ocular surgeries (except for cataract surgery more than 6 months ago) or other ocular diseases;
7. Bilateral moderate or severe cataracts;
8. Refractive errors of myopia, hyperopia and/or astigmatism more than 6.0 Diopters.
Minimum Eligible Age

65 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Joseph Signorile

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joseph F Signorile, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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Laboratory of Neuromuscular Research and Active Aging

Coral Gables, Florida, United States

Site Status

Laboratory of Neuromuscular Research and Active Aging

Coral Gables, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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20210271

Identifier Type: -

Identifier Source: org_study_id

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