Yoga Training and Retinal Vasculature

NCT ID: NCT06099405

Last Updated: 2025-05-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 34 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-09-01
• Study Completion Date: 2025-05-15

Brief Summary

This study will compare the impact of a novel high-speed, cued yoga program to a standard yoga program on retinal microvasculature, cognition and neuromuscular function.

Conditions

Cognitive Change

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

High-speed, Cognitive Challenge Yoga

Participants in this group will receive high-speed yoga training for 24 consecutive weeks for a total of 72 training sessions.

Group Type: EXPERIMENTAL

High-speed, Cognitive Challenge Yoga

Intervention Type: BEHAVIORAL

Participants in this group will receive high-speed yoga with cuing 3 times per week for 24 consecutive weeks for a total of 72 training sessions of 1 hour duration. Subjects will move as quickly as possible from one pose to another.

Traditional Yoga

Participants will perform standard Hatha yoga with slow controlled speed movements for 24 consecutive weeks for a total of 72 training sessions.

Group Type: ACTIVE_COMPARATOR

Traditional yoga

Intervention Type: BEHAVIORAL

Participants will perform controlled speed Hatha yoga 3 times per week for 24 weeks for a total of 72 sessions of 1 hour duration.

Interventions

High-speed, Cognitive Challenge Yoga

Participants in this group will receive high-speed yoga with cuing 3 times per week for 24 consecutive weeks for a total of 72 training sessions of 1 hour duration. Subjects will move as quickly as possible from one pose to another.

Intervention Type: BEHAVIORAL

Traditional yoga

Participants will perform controlled speed Hatha yoga 3 times per week for 24 weeks for a total of 72 sessions of 1 hour duration.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. 60-90 years of age;

2. Montreal Cognitive Assessment (MoCA) > 23

3. no memory loss complaints

Exclusion Criteria

1. uncontrolled cardiovascular or neuromuscular diseases that prevent participation in a training program;

2. cerebrovascular disease;

3. documented HIV infection or other immunodeficiency syndrome;

4. any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, or other serious concomitant medical illness;

5. a history of ocular surgeries (except for cataract surgery more than 6 months ago) or other ocular diseases;

6. bilateral moderate or severe cataracts;

7. refractive errors of myopia, hyperopia and/or astigmatism more than 6.0 Diopters

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

McKnight Brain Research Foundation

UNKNOWN

Sponsor Role: collaborator

University of Miami

OTHER

Sponsor Role: lead

Responsible Party

Joseph Signorile

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Joseph F. Signorile, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

Laboratory of Neruomuscular Research and Active Aging

Coral Gables, Florida, United States

Countries

United States

Other Identifiers

20230735

Identifier Type: -

Identifier Source: org_study_id