Effect of 100% Orange Juice on Food Intake and Glycemic Response in Adults

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-01

Study Completion Date

2022-12-22

Brief Summary

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The purpose of this study is to determine the effects of 100% orange juice on short-term food intake (FI), satiety, post-prandial glycemia and mood in healthy adults. We hypothesize that the consumption of 100% orange juice in the pre-meal environment will improve satiety signals and mood, and suppress FI through its effect on post-prandial glycemia.

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Detailed Description

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A randomized within-subjects repeated measures design will be employed. Study visits will take place in the morning, separated one-week apart. At each session, participants will consume one of three treatments: 1) 100% orange juice; 2) orange flavoured drink; or 3) water. Glycemic response will be measured for 60 minutes (baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes and 60 minutes) post-treatment via finger prick. Blood glucose measures will also be provided over 24 hours via a Dexcom G6 continuous glucose monitoring (CGM) device. Subjective appetite, emotions and mood will be measured for 90 minutes min (baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes and 90 minutes) post-treatment. At 60 minutes, participants will consume an ad libitum pizza lunch to evaluate food intake. After lunch, participants will be sent home with a rest-of-the-day food intake sheet to record their snacks, meals, and beverages, as well as a physical activity log to record their physical activity for the rest of the day following test session completion.

Conditions

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Healthy Adult Glycemic Response Appetite

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Orange juice

Treatment beverage

Group Type EXPERIMENTAL

Orange juice

Intervention Type OTHER

Matched for volume (240 mL/ 8 oz) of other test beverages. 100% orange juice.

Orange flavoured drink

Treatment beverage

Group Type EXPERIMENTAL

Orange flavoured drink

Intervention Type OTHER

Matched for volume (240 mL/ 8 oz) of other test beverages. Orange flavoured drink

Water

Treatment beverage

Group Type EXPERIMENTAL

Water

Intervention Type OTHER

Matched for volume (240 mL/ 8 oz) of other test beverages. Water control

Interventions

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Orange juice

Matched for volume (240 mL/ 8 oz) of other test beverages. 100% orange juice.

Intervention Type OTHER

Orange flavoured drink

Matched for volume (240 mL/ 8 oz) of other test beverages. Orange flavoured drink

Intervention Type OTHER

Water

Matched for volume (240 mL/ 8 oz) of other test beverages. Water control

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* aged 18-45 years;
* within the healthy body mass index (BMI) range for adults of 18.5-24.9 kg/m2.

Exclusion Criteria

* individuals who are dieting;
* restrained eaters;
* breakfast skippers;
* those who dislike breakfast or lunch treatment foods;
* those taking medication;
* individuals with any metabolic disorders or significant weight fluctuations.

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes