Effects of Low Calorie Sweeteners on Dietary Intakes, Hunger, Appetite and Satiety

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

170 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Although there is evidence that low calorie sweeteners (LCS) do not stimulate hunger or appetite, divergent opinions appear regularly both in the scientific literature and in the popular press. The goal of this study is to examine the effects of LCS containing beverages on appetite and intake in healthy individuals.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Low-calorie Sweeteners and Adipose Signaling

NCT03125356

Nutritional and Metabolic Diseases

COMPLETED NA

Neurological Impacts of Artificial Sweeteners in the Context of Diet Sodas

NCT04048681

Obesity

COMPLETED NA

The Effect of Sugar Sweetened and Diet Beverages Consumed as Part of a Weight-Maintenance Diet on Fat Storage

NCT02252952

Focus: Understanding the Obesogenic Potential of Sugars and Non-caloric Sweeteners

UNKNOWN NA

Low Calorie Sweeteners Effects on Appetite

NCT07018921

Appetite

COMPLETED NA

The Effects of Beverages on Food Liking

NCT03579043

Obesity

WITHDRAWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study will be a monocentric randomized controlled open trial including two parallel groups to examine effects of LCS beverages as compared to water on daily intakes of energy and macronutrients. The effects of LCS beverages on hunger, satiety, desire to eat and on the selection of sweet or savory foods eating occasions will be assessed.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Eating Behavior

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Beverage containing low calorie sweeteners

Beverage containing low calorie sweeteners (flavour)

Group Type EXPERIMENTAL

Beverage containing low calorie sweeteners

Intervention Type OTHER

Beverage containing low calorie sweeteners

Still water

Still water (no flavour)

Group Type ACTIVE_COMPARATOR

Still water

Intervention Type OTHER

Still water (no flavour)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Beverage containing low calorie sweeteners

Intervention Type OTHER

Still water

Still water (no flavour)

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Body Mass Index: Lower limit 18 kg/m²; Upper limit 28 kg/m²; weight stable within ± 3 kg in the last 6 months
* Habitual energy intake within the 95% confident interval of the reference energy intake for the French population (as provided by the INCA 2 survey
* Must not be a regular drinker of LCS beverages (less than once a week no more than every 15 days) and be willing to use LCS according to protocol
* For female participants: not pregnant, not breast feeding, planning to become pregnant during the study or on contraception since at least 3 months (regular 28-day cycle)
* Subject registered with the French Social Security.

Exclusion Criteria

* Currently diagnosed somatic pathology
* On medication affecting metabolism, weight, energy intake, or energy expenditure in the last 6 months
* Major psychiatric disorder, particularly eating disorders as defined by the Diagnostic and Statistical Manual od Mental Disorders-IV
* Rejection of sweet foods or drinks as revealed by the diet history
* Smoking subject planning to stop smoking in the next 3 months
* Subjects suffering from food allergies or intolerance
* Subject not capable of understanding the constraints of the study and who not agree to abide

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes