Investigating the Consumption of Different Protein Rich Whole Food Sources on Muscle Growth in Trained Males and Females

NCT ID: NCT04794153

Last Updated: 2024-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-01

Study Completion Date

2024-05-01

Brief Summary

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Background To date, most of the literature investigating the role of dietary protein in muscle growth has focused on isolated protein sources. However, dietary protein is most commonly consumed within a whole food source. Consuming dietary protein within a whole food matrix may additionally stimulate muscle growth. The idea being, there may be other components within food, capable of producing a greater response.

Objectives: To assess the effect of consuming a variety of whole food sources, on the stimulation of muscle growth compared to an isolated protein source following a single bout of lower body resistance exercise.

Methods Young healthy resistance-trained volunteers will consume a protein rich whole food source, following a bout of lower body resistance exercise. Stable isotope IV infusions and repeated blood and muscle samples will be taken to assess protein digestion and absorption, as well as muscle protein synthesis rates.

Value of Research:

To determine whether whole food sources potentiate muscle protein synthesis rates (and to what extent across whole food sources) compared to an isolated protein source. In doing so, we can further investigate the nutrients involved that may be contributing to this effect.

Detailed Description

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Conditions

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Nutritional Intervention Using Protein Rich Whole Food Sources

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Pork

Locally sourced

Group Type EXPERIMENTAL

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Salmon

Locally sourced

Group Type EXPERIMENTAL

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Mycoprotein

Provided by Marlow Foods

Group Type EXPERIMENTAL

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Lentils

Red

Group Type EXPERIMENTAL

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Egg

Local supplier

Group Type EXPERIMENTAL

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Egg whites

Local Supplier

Group Type ACTIVE_COMPARATOR

whole food sources

Intervention Type DIETARY_SUPPLEMENT

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Interventions

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whole food sources

Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Males and Females
* BMI 18.5 - 30 kg/m2
* Aged 18 - 40 years
* Structured Resistance training consistently for \> 6 months
* A 5-7 day "washout" period from any supplementation

Exclusion Criteria

* Age \>40 years
* Body mass index (BMI) \<18.5 or \>30 kg/m2
* Any metabolic impairments
* Any cardiovascular impairments
* High blood pressure (≥140/90 mmHg)
* Any gastrointestinal disorders
* Any medications known to affect protein and/or amino acid metabolism
* A personal or family history of epilepsy, seizures or schizophrenia, motor disorder
* Chronic over the counter use of pharmaceuticals (\> 1 month)
* Allergic to any of the whole foods included in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Marlow Foods Ltd

UNKNOWN

Sponsor Role collaborator

University of Exeter

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Professor Wall

Role: PRINCIPAL_INVESTIGATOR

University of Exeter

Locations

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University of Exeter

Exeter, Devon, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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FFT

Identifier Type: -

Identifier Source: org_study_id

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