The Effect of Food Supplements on Food Intake and Gut Hormone Levels

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-22

Study Completion Date

2019-07-22

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating. When people gain weight and become overweight or obese, these hormone signals are reduced, resulting in these people eating more and gaining more weight. This study is investigating mechanisms which may break this cycle by using particular nutrients to restore reduced hormone levels.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Impact of ß-glucan Supplementation on Subjective Appetite and Gastrointestinal Appetite Hormones.

NCT05981404

Overweight and Obesity

UNKNOWN NA

Effect of Medium Chain Triglyceride Consumption on Appetite

NCT01952977

Obesity

COMPLETED NA

Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity

NCT05822167

Obesity, Overweight

COMPLETED NA

Impact of Macronutrient Composition of Energy-restricted Diet and Exercise on Body Composition and Appetite Hormones.

NCT06022315

Gastrointestinal Hormones

RECRUITING NA

Evaluation of Botanicals for Mechanisms Related to Appetite and Fat Metabolism

NCT02333461

Overweight Obesity

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obesity Endocrine; Obesity Appetite; Perverted

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Double blinded, randomised, crossover, placebo controlled.

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo

Administered at time 0 min and 300 min. Cellulose was used as the placebo.

Group Type PLACEBO_COMPARATOR

Lauric Acid, Perilla Oil and Diindolylmethane

Intervention Type DIETARY_SUPPLEMENT

Colonic release capsules containing lauric acid (2400mg), perilla oil (2100mg) and diinodlylmethane (500mg) given to volunteers 1 hour prior to standardised breakfast and lunch meal. Placebo group given cellulose capsules of same volume prior to standardised breakfast and lunch meal.

Dietary Supplement

Administered at 0 min and 300 min. Combination of lauric acid, perilla oil and diindolylmethane was used as the dietary supplement.

Group Type ACTIVE_COMPARATOR

Lauric Acid, Perilla Oil and Diindolylmethane

Intervention Type DIETARY_SUPPLEMENT

Colonic release capsules containing lauric acid (2400mg), perilla oil (2100mg) and diinodlylmethane (500mg) given to volunteers 1 hour prior to standardised breakfast and lunch meal. Placebo group given cellulose capsules of same volume prior to standardised breakfast and lunch meal.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Lauric Acid, Perilla Oil and Diindolylmethane

Colonic release capsules containing lauric acid (2400mg), perilla oil (2100mg) and diinodlylmethane (500mg) given to volunteers 1 hour prior to standardised breakfast and lunch meal. Placebo group given cellulose capsules of same volume prior to standardised breakfast and lunch meal.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Obese but otherwise healthy volunteers,
* body mass index (BMI) of 30-40 kg/m2
* agreement to consume scheduled meals
* ability to understand the study information sheet and instructions in English and able to provide informed consent.