Effect of Medium Chain Triglyceride Consumption on Appetite

NCT ID: NCT01952977

Last Updated: 2013-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2011-08-31

Brief Summary

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The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.

Detailed Description

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Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Participants

Study Groups

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MCT

MCT oil (20 g) was included in the test breakfast

Group Type ACTIVE_COMPARATOR

Test breakfast

Intervention Type DIETARY_SUPPLEMENT

LCT

Corn oil (20 g) was included in the test breakfast

Group Type PLACEBO_COMPARATOR

Test breakfast

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Test breakfast

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Males
* Weight stable (\<10 lb over previous 3 months)
* Overweight (body mass index 25-29.9)

Exclusion Criteria

* Smokers
* Excessive caffeine users
* Severe health conditions
* Allergy to food products/ingredients in the study
* Taking medications known to affect energy expenditure or gastrointestinal function
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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St. Luke's-Roosevelt Hospital Center

OTHER

Sponsor Role lead

Responsible Party

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Marie-Pierre St-Onge

Research Associate

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marie-Pierre St-Onge, Ph.D

Role: PRINCIPAL_INVESTIGATOR

New York Obesity Nutrition Research Center

Locations

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New York Obesity Nutrition Research Center

New York, New York, United States

Site Status

Countries

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United States

References

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St-Onge MP, Mayrsohn B, O'Keeffe M, Kissileff HR, Choudhury AR, Laferrere B. Impact of medium and long chain triglycerides consumption on appetite and food intake in overweight men. Eur J Clin Nutr. 2014 Oct;68(10):1134-40. doi: 10.1038/ejcn.2014.145. Epub 2014 Jul 30.

Reference Type DERIVED
PMID: 25074387 (View on PubMed)

Other Identifiers

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MCT_1

Identifier Type: -

Identifier Source: org_study_id