Effects of Learning and Food Form on Intake in Humans

NCT ID: NCT01490034

Last Updated: 2015-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2015-05-31

Brief Summary

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Due to the rising incidence of obesity, much emphasis has been placed on identifying mechanisms of increased energy intake. At this point, the mechanisms responsible for the recent increase in obesity prevalence have not been thoroughly examined. Pre-ingestive influences, such as cognitive factors, may play a larger role in creating an energy surplus than previously thought. Expectations about the satiating effect of a food may override the post-ingestive influences in dictating further consumption. In addition, obese individuals may exhibit a decreased compensatory response to foods as compared to lean individuals.

Understanding the effects of energy content, food form, and learning on satiation, satiety, and energy intake will allow for a greater understanding of the mechanisms of energy imbalance as a whole. Food choice is dictated by sensory properties and post-ingestive effects. By utilizing foods with similar sensory properties, the acquired knowledge derived from ingesting these foods can be monitored by analyzing subsequent intake at the same meal and at subsequent eating occurrences. It is hypothesized that the liquid food form will elicit weaker dietary compensation; that is, energy intake at other eating events will not be adjusted to compensate for that food. In addition, it is posited that the lower energy food will cause lower compensation postprandially. By having participants consume the same test food daily over a two week learning period, it is thought that they will show improved dietary compensation when the initial testing is repeated due to learned associations between food properties and metabolism.

Detailed Description

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No expansion provided.

Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Energy dense beverage

Metabolic effects of consuming energy dense beverages before and after regular consumption

Group Type EXPERIMENTAL

Metabolic effects of consuming energy dense beverages

Intervention Type BEHAVIORAL

Consumption of energy dense beverages for 2 weeks and monitoring physiological responses

Energy dense solid food form

Metabolic effects of consuming energy dense solid foods before and after regular exposure.

Group Type EXPERIMENTAL

energy dense solid food

Intervention Type BEHAVIORAL

Effects of consuming energy dense solid food for two weeks on physiological responses

Eenergy dilute beverages

Metabolic effects of consumption of energy dilute beverages on a regular basis.

Group Type EXPERIMENTAL

Energy dilute beverages

Intervention Type BEHAVIORAL

Effects of consuming energy dilute beverages for two weeks on physiological responses.

Energy dilute solid food form

Metabolic effects of consuming energy dilute sold foods before and after regular exposure.

Group Type EXPERIMENTAL

Energy dilute solid food

Intervention Type BEHAVIORAL

Effects of consuming energy dilute solid food for two weeks on physiological responses

Interventions

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Metabolic effects of consuming energy dense beverages

Consumption of energy dense beverages for 2 weeks and monitoring physiological responses

Intervention Type BEHAVIORAL

energy dense solid food

Effects of consuming energy dense solid food for two weeks on physiological responses

Intervention Type BEHAVIORAL

Energy dilute beverages

Effects of consuming energy dilute beverages for two weeks on physiological responses.

Intervention Type BEHAVIORAL

Energy dilute solid food

Effects of consuming energy dilute solid food for two weeks on physiological responses

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Weight stable (\<3 kg weight change within last 3 months)
* Constant habitual activity patterns (no deviation \> 1x/wk at 30 min/session within last 3 months)
* Constant habitual diet patterns within last 3 months
* Willingness to eat a chocolate-flavored snack at test sessions and two week training period
* No allergies to any test foods
* Not planning to change use of medications known to influence appetite or metabolism
* Not diabetic
* No history of GI pathology
* Non-smoker for one year or more
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Purdue University

OTHER

Sponsor Role lead

Responsible Party

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Richard Mattes

Distinguished Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Purdue Univeristy

West Lafayette, Indiana, United States

Site Status

Countries

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United States

References

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Jones JB, Mattes RD. Effects of learning and food form on energy intake and appetitive responses. Physiol Behav. 2014 Oct;137:1-8. doi: 10.1016/j.physbeh.2014.06.016. Epub 2014 Jun 21.

Reference Type DERIVED
PMID: 24955495 (View on PubMed)

Other Identifiers

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R01DK079913

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R01DK079913-3

Identifier Type: -

Identifier Source: org_study_id

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