Creatine Supplementation and Cognitive and Physical Tests

NCT ID: NCT03352128

Last Updated: 2019-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-10

Study Completion Date

2019-03-28

Brief Summary

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To assess whether brain creatine availability has an effect on cognition. To do so we will seek to increase brain creatine concentration via a creatine supplementation protocol.

Detailed Description

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Conditions

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Healthy Creatine Supplementation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Creatine supplementation

7-day creatine supplementation

Group Type EXPERIMENTAL

Creatine

Intervention Type DIETARY_SUPPLEMENT

Participants will have to supplement themselves with creatine for 7 days (20g/day).

Placebo supplementation

7-day calcium lactate supplementation

Group Type PLACEBO_COMPARATOR

Calcium lactate

Intervention Type DIETARY_SUPPLEMENT

Participants will have to supplement themselves with calcium lactate for 7 days (elemental calcium: 0.780g/day).

Interventions

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Creatine

Participants will have to supplement themselves with creatine for 7 days (20g/day).

Intervention Type DIETARY_SUPPLEMENT

Calcium lactate

Participants will have to supplement themselves with calcium lactate for 7 days (elemental calcium: 0.780g/day).

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy (No neurological illness including cardiovascular, renal, and endocrine disorder)
* Male/female
* No medication / supplements
* Non-smoker
* Low to moderately active
* Between 18 and 35 years old

Exclusion Criteria

* Injuries
* Illness
* Use of medication
* Use of creatine in the last 3 months
* History of head trauma or seizure
* Vegetarian diet \[24\]
* Not being able to follow up the restrictions and prohibitions for the subjects (see Restrictions and prohibitions for the subjects)
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Vrije Universiteit Brussel

OTHER

Sponsor Role lead

Responsible Party

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Romain Meeusen

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Human Physiology and Sports Physiotherapy Research Group

Brussels, , Belgium

Site Status

Countries

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Belgium

Other Identifiers

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CREA

Identifier Type: -

Identifier Source: org_study_id

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