Effect of Increased Protein Intake on Colonic Metabolism

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-10-31

Brief Summary

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The purpose of this study is to modulate the protein fermentation and to investigate the effect on colon toxicity.

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Detailed Description

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Conditions

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Protein Fermentation Toxicity in the Colon

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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High Protein intake

Group Type EXPERIMENTAL

High protein intake

Intervention Type DIETARY_SUPPLEMENT

30% of energy intake coming from proteins

Low Protein intake

Group Type EXPERIMENTAL

Low Protein intake

Intervention Type DIETARY_SUPPLEMENT

9% of energy intake coming from proteins

Interventions

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High protein intake

30% of energy intake coming from proteins

Intervention Type DIETARY_SUPPLEMENT

Low Protein intake

9% of energy intake coming from proteins

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Regular eating pattern (3 meals/day)
* Age between 18 and 45 years old
* BMI between 18,5 and 30 kg/m²

Exclusion Criteria

* Intake of antibiotics in the last month before the study
* Abdominal surgeries in the past (accept appendectomy)
* Consulting a dietician/following a diet
* Vegetarian
* Intake of pre- and/or probiotics
* Exposure to radioactivity in the year proceeding the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes