Exercise in the Fasted State, Glucose Metabolism and Energy Balance

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2017-12-31

Brief Summary

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The ability to control our blood glucose (sugar) concentrations after a meal is a strong predictor of the risk of disease. Our bodies respond to glucose ingestion by reducing the amount of glucose from the liver entering the bloodstream. At the same time muscle increases the amount of glucose it take up from the bloodstream. This ensures that our blood glucose levels do not get too high. The investigators want to understand what happens to these processes following exercise after breakfast and after an overnight fast. In addition, the investigators also want to understand whether exercising with or without breakfast influences our appetite, food intake and activity levels later in the day.

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Detailed Description

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Conditions

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Energy Balance Blood Glucose

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Breakfast Rest

Group Type ACTIVE_COMPARATOR

Breakfast

Intervention Type DIETARY_SUPPLEMENT

Breakfast consumption

Breakfast Exercise

Group Type ACTIVE_COMPARATOR

Exercise

Intervention Type BEHAVIORAL

Moderate intensity exercise

Breakfast

Intervention Type DIETARY_SUPPLEMENT

Breakfast consumption

Fasted Exercise

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Moderate intensity exercise

Interventions

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Exercise

Moderate intensity exercise

Intervention Type BEHAVIORAL

Breakfast

Breakfast consumption

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Males.
* Aged 18-49.
* Individuals free from known cardiovascular, metabolic or joint disease as determined by standard health questionnaire.
* Habitual regularly participating in exercise (minimum of 3 sessions per week on average)
* Non-smoker

Exclusion Criteria

* Known or suspected food intolerances, allergies or hypersensitivity.
* Any bleeding disorder or taking medication which impacts blood coagulation.
* Known tendency towards keloid scarring.
* Known sensitivity or allergy to any local anaesthetic medicines.
* Any reported use of substances which may pose undue personal risk to participants or introduce bias into the experiment.
* Any other condition or behaviour deemed either to pose undue personal risk to participants or introduce bias into the experiment.

Minimum Eligible Age

18 Years

Maximum Eligible Age

49 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes