Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.

NCT ID: NCT01987687

Last Updated: 2014-08-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

SUSPENDED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-30

Study Completion Date

2017-04-30

Brief Summary

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Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality.

Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.

Detailed Description

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Conditions

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Area Under Curve [N06.850.520.830.200]

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Rest

Breakfast followed by a rest period prior to OGTT.

Group Type ACTIVE_COMPARATOR

Rest

Intervention Type BEHAVIORAL

Rest for 30 min

Exercise-immediate

Breakfast followed by exercise and an immediate OGTT

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Exercise at 55% of maximum power output for 30 min.

Exercise-delay

Breakfast followed by exercise and a delayed (1 h) OGTT.

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Exercise at 55% of maximum power output for 30 min.

Delay

Intervention Type BEHAVIORAL

Delay between exercise and OGTT

Interventions

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Exercise

Exercise at 55% of maximum power output for 30 min.

Intervention Type BEHAVIORAL

Rest

Rest for 30 min

Intervention Type BEHAVIORAL

Delay

Delay between exercise and OGTT

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Normal weight (18-25 kg/m2)
* Physically active (\>or= 3 times per week)
* Male

Exclusion Criteria

* Contraindications to exercise
* Food intolerances
* Food allergies
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Northumbria University

OTHER

Sponsor Role lead

Responsible Party

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Javier Gonzalez, PhD

Research Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Javier T Gonzalez, PhD

Role: PRINCIPAL_INVESTIGATOR

Northumbria University

Locations

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Northumbria University

Newcastle upon Tyne, Tyne and Wear, United Kingdom

Site Status

Countries

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United Kingdom

References

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Gonzalez JT, Stevenson EJ. Assessment of the post-exercise glycemic response to food: considering prior nutritional status. Nutrition. 2014 Jan;30(1):122-3. doi: 10.1016/j.nut.2013.05.015. Epub 2013 Sep 18. No abstract available.

Reference Type BACKGROUND
PMID: 24054351 (View on PubMed)

Gonzalez JT, Veasey RC, Rumbold PL, Stevenson EJ. Breakfast and exercise contingently affect postprandial metabolism and energy balance in physically active males. Br J Nutr. 2013 Aug;110(4):721-32. doi: 10.1017/S0007114512005582. Epub 2013 Jan 29.

Reference Type BACKGROUND
PMID: 23340006 (View on PubMed)

Other Identifiers

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32W7

Identifier Type: -

Identifier Source: secondary_id

32W7

Identifier Type: -

Identifier Source: org_study_id