Food Orders on Blood Glucose and Fuel Use At Rest

NCT ID: NCT06763562

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-05

Study Completion Date

2026-06-30

Brief Summary

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Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls. However, gaps remain in the literature in this area of research, and currently little is known about how substrate (fuel) use is impacted by altering food order. In addition, most studies to date have used a mix of meat and plant foods, while little research has focused exclusively on vegetarian foods. This randomized experiment will examine how altering the order of foods eaten in a vegetarian meal impacts blood glucose and fuel utilization at rest.

Detailed Description

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Conditions

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Glucose Metabolism Disorders Hunger Fat Burn

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Carbohydrate-first meal

Group Type EXPERIMENTAL

Carbohydrate-first meal

Intervention Type OTHER

Rice eaten first (150 grams), followed by edamame (150 grams) and butter (10 grams)

Carbohydrate-last meal

Group Type EXPERIMENTAL

Carbohydrate-last meal

Intervention Type OTHER

Edamame (150 grams) and butter (10 grams) eaten first, followed by rice (150 grams)

Interventions

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Carbohydrate-first meal

Rice eaten first (150 grams), followed by edamame (150 grams) and butter (10 grams)

Intervention Type OTHER

Carbohydrate-last meal

Edamame (150 grams) and butter (10 grams) eaten first, followed by rice (150 grams)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18-70 years old
* Free from any allergy or condition that precluding consumption of edamame, butter, and rice
* Not currently pregnant
* Free of any medical conditions requiring the use of insulin
* Have no history of bariatric surgery
* Have no implanted electrical devices such as a pacemaker

Exclusion Criteria

* Younger than 18 and older than 70 years old
* Having an allergy or condition that precludes consumption of edamame, butter, and rice
* Currently pregnant
* Any medical conditions requiring the use of insulin
* A history of bariatric surgery
* Having an implanted electrical device such as a pacemaker
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Old Dominion University

OTHER

Sponsor Role lead

Responsible Party

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Patrick Wilson, PhD

Associate Professor of Exercise Science

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Old Dominion University Human Performance Laboratory

Norfolk, Virginia, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Patrick Wilson, PhD

Role: CONTACT

757-683-4783

Facility Contacts

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Patrick Wilson, PhD

Role: primary

Other Identifiers

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24-163

Identifier Type: -

Identifier Source: org_study_id

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