Short-term Effect of Glucose and Sacharose Ingestion on Cognitive Performance and Mood in Elderly

NCT ID: NCT01427231

Last Updated: 2012-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

43 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2011-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of the current study is to determine the acute effect of a glucose drink and a sacharose drink compared to a placebo on cognitive performance in elderly with light memory complaints. The investigators expect that the sugar containing drinks will improve memory and attentional functions. Furthermore, blood glucose response will be measured.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mental Health Cognition Memory Attention

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Drink with 50 g glucose

The glucose drink contains 50 g of glucose soluted in 250 ml of water and lemon juice.

Group Type ACTIVE_COMPARATOR

glucose

Intervention Type DIETARY_SUPPLEMENT

The effect of a glucose solution on cognitive performance will be measured.

Drink with 100 gram of sacharose

The sacharose drink contains 100 g of sacharose soluted in 250 ml of water and lemon juice.

Group Type ACTIVE_COMPARATOR

sacharose

Intervention Type DIETARY_SUPPLEMENT

The effect of a sacharose solution on cognitive performance will be measured.

Placebo with sweeteners

The placebo contains a mixture of artificial sweeteners in order to have the same sweetness and appearance of the test drinks (the glucose drink and the sacharose drink).

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

The effect of a placebo drink with sweeteners on cognitive performance will be measured.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

glucose

The effect of a glucose solution on cognitive performance will be measured.

Intervention Type DIETARY_SUPPLEMENT

sacharose

The effect of a sacharose solution on cognitive performance will be measured.

Intervention Type DIETARY_SUPPLEMENT

Placebo

The effect of a placebo drink with sweeteners on cognitive performance will be measured.

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Sucrose, sugar.

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men and women
* 70 years and older
* Memory complaints

Exclusion Criteria

* Type I or II diabetes
* Parkinson disease
* MMSE \< 25 (to exclude cognitively impaired subjects
* CES-D \> 16 (to exclude depressive subjects)
* Pharmacological antidepressives or medication for dementia
* Liver disease
Minimum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Suikerstichting Nederland (Baarn)

UNKNOWN

Sponsor Role collaborator

Wageningen University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Lisette de Groot

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Wageningen University

Wageningen, Gelderland, Netherlands

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Netherlands

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NL36813.081.11

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.