The Effect of the Glycemic Load of Meals on the Cognition and Mood of Older Adults
NCT ID: NCT01842022
Last Updated: 2014-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
155 participants
INTERVENTIONAL
2011-09-30
2013-09-30
Brief Summary
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As older adults have a higher incidence of glucose tolerance and are more likely to experience memory problems the present study considers the interaction between the GL of meal in those with better or poorer GT.
The population studied will not have a history of diabetes or dementia. A battery of cognitive tests will be administered after meals sweetened with one of three sugars known to vary in the rate that they release glucose into the blood stream.
Detailed Description
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On a second occasion 155 healthy older adults, aged 45-80 years, will be randomly assigned to receive either a glucose, sucrose or isomaltulose based meal. All meals are matched on macronutrient composition and differ only in glycemic load. Cognitive performance and mood will be assessed 30, 105 and 180 minutes after breakfast. Measures of memory, attention, reaction times and mood will be taken.
The response to the three meals will be contrasted in those with different glucose profiles on day one
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
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Better glucose tolerance
Take meals with isomaltulose, sucrose or glucose
Isomaltulose
Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Sucrose
Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Glucose
Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Better glucose tolerance / Levels fall
Take meals with isomaltulose, sucrose or glucose
Isomaltulose
Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Sucrose
Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Glucose
Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Poorer tolerance levels remain high
Take meals with isomaltulose, sucrose or glucose
Isomaltulose
Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Sucrose
Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Glucose
Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Poorer glucose tolerance / Levels fall
Take meals with isomaltulose, sucrose or glucose
Isomaltulose
Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Sucrose
Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Glucose
Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Interventions
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Isomaltulose
Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Sucrose
Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Glucose
Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Dementia
* Liver disease
* Gastro-intestinal problems
45 Years
80 Years
ALL
Yes
Sponsors
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Swansea University
OTHER
Responsible Party
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David Benton
Professor of Psychology
Principal Investigators
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David Benton, DSc
Role: PRINCIPAL_INVESTIGATOR
Swansea University
Locations
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Psychology, Swansea University
Swansea, Wales, United Kingdom
Countries
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Other Identifiers
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DB-0413
Identifier Type: -
Identifier Source: org_study_id