Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia

NCT ID: NCT00935571

Last Updated: 2009-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-10-31

Study Completion Date

2009-09-30

Brief Summary

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The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.

Detailed Description

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Thoracotomy is one of the most painful surgical incisions. It has been shown that 5-80% of patients still suffer from thoracic pain 2-3 months after surgery and the international association for the study of pain (IASP) defines postthoracotomy pain syndrome (PTTS)as pain that recurs or persists at least 2 months after surgical procedure. Previous reports have shown that the incidence of PTTS varies according to preoperative pain, pain intensity, sex, and types of procedure. However, little is known about the effect of the type of anesthesia to postthoracotomy pain.

Conditions

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Lung Cancer Neoplasms, Lung

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Group I, Group II

Group I: anesthetized with TIVA (Propofol + Remifentanil)

Group II: anesthetized with inhalation (sevoflurane)

propofol, remifentanil, sevoflurane

Intervention Type DRUG

Propofol: using target controlled infusion (TCI); 1-3ug/ml remifentanil: using TCI by 5-20 ng/ml sevoflurane: 2-3volume% (1-2 MAC)

Interventions

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propofol, remifentanil, sevoflurane

Propofol: using target controlled infusion (TCI); 1-3ug/ml remifentanil: using TCI by 5-20 ng/ml sevoflurane: 2-3volume% (1-2 MAC)

Intervention Type DRUG

Other Intervention Names

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diprivan ultiva

Eligibility Criteria

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Inclusion Criteria

* patients undergo elective thoracotomy of lung surgery

Exclusion Criteria

* emergency operation age under 18 years patients with unstable hemodynamics
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Asan Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Asan Medical Center

Principal Investigators

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In Cheol Choi, MD, PhD

Role: STUDY_CHAIR

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine

Locations

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Department of Anesthesiology and Pain Medicine, University of Ulsan College of Medicine, Asan Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Gotoda Y, Kambara N, Sakai T, Kishi Y, Kodama K, Koyama T. The morbidity, time course and predictive factors for persistent post-thoracotomy pain. Eur J Pain. 2001;5(1):89-96. doi: 10.1053/eujp.2001.0225.

Reference Type BACKGROUND
PMID: 11394926 (View on PubMed)

Other Identifiers

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20090708

Identifier Type: -

Identifier Source: org_study_id

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