Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40

NCT ID: NCT01760018

Last Updated: 2014-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

76 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-12-31

Study Completion Date

2013-01-31

Brief Summary

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Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire.

Detailed Description

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Conditions

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Thyroid Operation Under General Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Desflurane group

Group Type EXPERIMENTAL

desflurane group

Intervention Type DRUG

anesthesia is maintained with desflurane and remifentanil (Desflurane group)

TIVA(total intravenous anesthesia) group

Group Type ACTIVE_COMPARATOR

TIVA group

Intervention Type DRUG

anesthesia is maintained with fresofol and remifentanil (TIVA group).

Interventions

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desflurane group

anesthesia is maintained with desflurane and remifentanil (Desflurane group)

Intervention Type DRUG

TIVA group

anesthesia is maintained with fresofol and remifentanil (TIVA group).

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients who are undergoing thyroid operation belong to ASA class 1 or 2

Exclusion Criteria

* patients who are belongs to ASA class 3 or more,
* patients who have underlying complicated cardiovascular or psychological disease.
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Severance Hospital

Seoul, Seoul, South Korea

Site Status

Countries

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South Korea

References

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Myles PS, Weitkamp B, Jones K, Melick J, Hensen S. Validity and reliability of a postoperative quality of recovery score: the QoR-40. Br J Anaesth. 2000 Jan;84(1):11-5. doi: 10.1093/oxfordjournals.bja.a013366.

Reference Type BACKGROUND
PMID: 10740540 (View on PubMed)

Lee WK, Kim MS, Kang SW, Kim S, Lee JR. Type of anaesthesia and patient quality of recovery: a randomized trial comparing propofol-remifentanil total i.v. anaesthesia with desflurane anaesthesia. Br J Anaesth. 2015 Apr;114(4):663-8. doi: 10.1093/bja/aeu405. Epub 2014 Dec 10.

Reference Type DERIVED
PMID: 25500679 (View on PubMed)

Other Identifiers

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4-2012-0748

Identifier Type: -

Identifier Source: org_study_id

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