Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery
NCT ID: NCT01189721
Last Updated: 2010-08-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
84 participants
INTERVENTIONAL
2010-08-31
2011-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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sevoflurane
Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min. patients who are in this group will be infused propofol intraoperatively.
propofol, sevoflurane
Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min (group1 and 2) group 1 (Active Comparator, sevoflurane)will be infused propofol intraoperatively.
group 2(Experimental, propofol) will be inhaled sevoflurane intraoperatively.
propofol
Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min. patients included this group will be inhaled sevoflurane intraoperatively.
propofol, sevoflurane
Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min (group1 and 2) group 1 (Active Comparator, sevoflurane)will be infused propofol intraoperatively.
group 2(Experimental, propofol) will be inhaled sevoflurane intraoperatively.
Interventions
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propofol, sevoflurane
Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min (group1 and 2) group 1 (Active Comparator, sevoflurane)will be infused propofol intraoperatively.
group 2(Experimental, propofol) will be inhaled sevoflurane intraoperatively.
Eligibility Criteria
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Inclusion Criteria
* Age 20-65
* American Society of Anesthesiologists physical status classification I or II
Exclusion Criteria
* History of drug \& alcohol abuse
* Psychiatric disorder
* Use of opioids within 24hrs
* Renal disease with decreased glomerular filtrate ratio
* Neuromuscular disease, Severe cardiac disease
20 Years
65 Years
ALL
No
Sponsors
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Gangnam Severance Hospital
OTHER
Responsible Party
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Anesthesia and Pain Research Institute
Principal Investigators
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yuen hee shim, MD
Role: STUDY_CHAIR
Gangnam severance hospital, Yonsei university, Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Reseach Institute
Locations
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Gang Nam Severance Hospital, Yonsei University, Anesthesia and Pain Medicine Department,
Seoul, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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3-2010-0102
Identifier Type: -
Identifier Source: org_study_id
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