Effects of Systemic Lidocaine on Postoperative Quality of Recovery After Robot-assisted Thyroidectomy

NCT ID: NCT01907997

Last Updated: 2015-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2015-05-31

Brief Summary

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Systemic lidocaine infusion may improve the patients' recovery quality and chronic post surgical pain after robot-assisted thyroidectomy

Detailed Description

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Conditions

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Thyroid Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Group L

Intravenous lidocaine infusion group

Group Type EXPERIMENTAL

Systemic intravenous lidocaine infusion

Intervention Type DRUG

In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.

Group C

Intravenous normal saline infusion - control group

Group Type PLACEBO_COMPARATOR

normal saline infusion

Intervention Type DRUG

In group C, the patients receive same volume of normal saline

Interventions

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Systemic intravenous lidocaine infusion

In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.

Intervention Type DRUG

normal saline infusion

In group C, the patients receive same volume of normal saline

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age between 20-65
* ASA class I and II
* Thyroid cancer patients who are scheduled for elective robot-assisted thyroidectomy

Exclusion Criteria

* Allergy to local anesthetics or contraindication to use of lidocaine
* Pregnancy
* Severe cardiovascular disease
* Renal failure
* Liver failure
* Neurologic and psychologic disease
* Chronic treatment with analgesics
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei universiy college of medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Choi KW, Nam KH, Lee JR, Chung WY, Kang SW, Joe YE, Lee JH. The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study. World J Surg. 2017 May;41(5):1305-1312. doi: 10.1007/s00268-016-3842-1.

Reference Type DERIVED
PMID: 27896411 (View on PubMed)

Other Identifiers

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4-2013-0342

Identifier Type: -

Identifier Source: org_study_id

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