Simultaneous Injection of Propofol and Rocuronium in Inducing General Anesthesia
NCT ID: NCT03270696
Last Updated: 2018-04-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
114 participants
INTERVENTIONAL
2017-08-23
2018-01-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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simultaneous administration of propofol and rocuronium
In this group, the investigator will administrate propofol (2ml/kg) and rocuronium (0.6mg/kg) simultaneously, and start facemask ventilation after patient loss consciousness to induce general anesthesia.
The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.
administration of propofol and rocuronium
compare the tidal volume applied from starting facemask ventilation under 15cmH2O of PCV for 1 minute according to administrating propofol and rocuronium simultaneously, or ordinally
ordinal administration of propofol and rocuronium
In this group, the investigator will administrate propofol (2ml/kg) first, and follow injection of rocuronium (0.6mg/kg) after patient loss consciousness and confirming facemask ventilation.
The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.
administration of propofol and rocuronium
compare the tidal volume applied from starting facemask ventilation under 15cmH2O of PCV for 1 minute according to administrating propofol and rocuronium simultaneously, or ordinally
Interventions
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administration of propofol and rocuronium
compare the tidal volume applied from starting facemask ventilation under 15cmH2O of PCV for 1 minute according to administrating propofol and rocuronium simultaneously, or ordinally
Eligibility Criteria
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Inclusion Criteria
* ASA I, II, and III
* above 20 years
Exclusion Criteria
* patients with risk of aspirating gastric contents
* patients in whom NMBs are contraindicated
* patients with predictors of difficult mask ventilation
20 Years
ALL
No
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Jeong-Hwa Seo
Professor
Principal Investigators
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JH Seo
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
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Seoul National University Hospital
Seoul, , South Korea
Countries
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References
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Min SH, Im H, Kim BR, Yoon S, Bahk JH, Seo JH. Randomized Trial Comparing Early and Late Administration of Rocuronium Before and After Checking Mask Ventilation in Patients With Normal Airways. Anesth Analg. 2019 Aug;129(2):380-386. doi: 10.1213/ANE.0000000000004060.
Other Identifiers
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JHSeo_MV
Identifier Type: -
Identifier Source: org_study_id
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