Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Breast Cancer
NCT ID: NCT02567929
Last Updated: 2018-04-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
218 participants
INTERVENTIONAL
2016-03-31
2016-12-31
Brief Summary
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The purpose of this study is to prove the variation of immune cell activity between preoperative and postoperative period.
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Detailed Description
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1. immediate before anesthesia induction
2. postoperative 1 hours
3. postoperative 24 hours
Serum in blood will be obtained and activity of helper T cell, natural killer cell and level of serum cytokine will be evaluated by flow cytometry or enzyme-linked immunosorbent assay
Conditions
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Study Design
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RANDOMIZED
FACTORIAL
BASIC_SCIENCE
QUADRUPLE
Study Groups
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propofol group
The patient who anesthetized by using propofol.
propofol group
Patient will be anesthetized by using propofol infusion during operation.
sevoflurane group
The patient who anesthetized by using propofol
sevoflurane group
Patient will be anesthetized by using sevoflurane inhalation during operation.
Interventions
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propofol group
Patient will be anesthetized by using propofol infusion during operation.
sevoflurane group
Patient will be anesthetized by using sevoflurane inhalation during operation.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* history of hypersensitivity reaction in propofol or sevoflurane
* history of previous cancer
* patient with ongoing inflammation
20 Years
FEMALE
No
Sponsors
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Konkuk University Medical Center
OTHER
Responsible Party
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Seong-Hyop Kim
Associate Professor
Principal Investigators
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Seong-Hyop Kim, M.D,Ph.D
Role: PRINCIPAL_INVESTIGATOR
Konkuk University Medical Center
Locations
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Konkuk University Medical Center
Seoul, , South Korea
Countries
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Other Identifiers
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KUH1160086
Identifier Type: -
Identifier Source: org_study_id
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