The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients
NCT ID: NCT06353516
Last Updated: 2024-04-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
154 participants
INTERVENTIONAL
2024-02-14
2024-12-31
Brief Summary
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* \[Is the permeability of blood-brain barrier between the intravenous anesthesia group and the inhalation gas anesthesia group in the elderly patients different?\]
* \[Is the incidence of postoperative cognitive dysfunction between the intravenous anesthesia group and the inhalation gas anesthesia group different?\] Participants will be anesthetized with different categories of anesthetics.
* Intravenous anesthetics
* Inhalation gas anesthetics
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Intravenous Anesthesia
The anesthesia is maintained with intravenous anesthetics
Propofol
delivered via intravenous route
Inhaled Gas Anesthesia
The anesthesia is maintained with inhaled gas anesthetics
Sevoflurane
delivered via inhalation route
Interventions
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Propofol
delivered via intravenous route
Sevoflurane
delivered via inhalation route
Eligibility Criteria
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Inclusion Criteria
* american Society of Anesthesiologists (ASA) grade I to III
* general anesthesia longer than 2 hours
Exclusion Criteria
* history of schizophrenia, epilepsy, or Parkinson's disease
* history of stroke or craniectomy
* patient denial
60 Years
ALL
No
Sponsors
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National Research Foundation of Korea
OTHER
Chung-Ang University Gwangmyeong Hospital
OTHER
Responsible Party
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Eun Jung Oh
Assistant Professor
Principal Investigators
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Eun Jung Oh, M.D., Ph.D.
Role: STUDY_DIRECTOR
Chung-Ang University Gwangmyeong Hospital
Locations
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Chung-Ang University Gwangmyeong Hospital
Gwangmyeong, Gyeonggi-do, South Korea
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2310-117-126
Identifier Type: -
Identifier Source: org_study_id
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