Caffeine, Resistance Exercise and Muscle/Cerebral Oxygenation

NCT ID: NCT07001176

Last Updated: 2025-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-12-23

Brief Summary

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Introduction: Several studies have evaluated and confirmed the ergogenic effects of acute caffeine intake on sports performance. However, the mechanism responsible for this ergogenic effect remains to be elucidated.

Objectives: This study aims to evaluate the acute effects of caffeine intake on muscle and cerebral oxygen during muscular strength, power, muscle endurance performance. and muscle electrical activity in young adults.

Detailed Description

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Conditions

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Caffeine and Resistance Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators
Statistician

Study Groups

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Caffeine

Acute caffeine intake (3 mg/kg)

Group Type EXPERIMENTAL

Caffeine

Intervention Type DIETARY_SUPPLEMENT

Acute caffeine intake (3 mg/kg)

Placebo

Acute placebo intake

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Acute placebo intake (3 mg/kg)

Interventions

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Caffeine

Acute caffeine intake (3 mg/kg)

Intervention Type DIETARY_SUPPLEMENT

Placebo

Acute placebo intake (3 mg/kg)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 35 years.
* Body Mass Index (BMI) \< 25 kg/m².
* Resistance-trained individuals (more than 2 years of structured training).
* Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
* Participants must be able to perform the tests described in the following section.

Exclusion Criteria

* History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
* Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
* Sedentary habits (less than 150 minutes/week of moderate exercise).
* Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
* Engaging in strenuous exercise within 48 hours prior to the tests.
* Failure to replicate the same food intake on both experimental days.
* Consumption of caffeine or any other stimulant after 6 pm on the day before the tests, to avoid headaches, discomfort, or lethargy in regular caffeine consumers.
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Alcala

OTHER

Sponsor Role lead

Responsible Party

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Alberto Pérez-López

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

Alcalá de Henares, Madrid, Spain

Site Status

Countries

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Spain

Other Identifiers

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CEID/2023/3/070

Identifier Type: -

Identifier Source: org_study_id

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