Caffeine and Resistance Training in Older Adults

NCT ID: NCT06618261

Last Updated: 2024-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-14

Study Completion Date

2025-07-30

Brief Summary

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Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to strength training.

Objectives: The present study aims to analyze the effects of acute and chronic caffeine intake on neuromuscular adaptations to strength training, according to sex (men vs. women) and type of exercise (bench press vs. squat), as well as fatigue perception, mood state, and potential side effects in older adults.

Detailed Description

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Conditions

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Caffeine and Resistance Training

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled trial
Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Caffeine - Males

Group Type EXPERIMENTAL

Caffeine + Resistance exercise

Intervention Type DIETARY_SUPPLEMENT

Acute caffeine intake (3 mg/kg) prior each resistance training session of a 8 weeks training program.

Placebo - Males

Group Type PLACEBO_COMPARATOR

Placebo + Resistance exercise

Intervention Type DIETARY_SUPPLEMENT

Acute placeb intake (3 mg/kg of maltodextrin) prior each resistance training session of a 8 weeks training program.

Caffeine - Females

Group Type EXPERIMENTAL

Caffeine + Resistance exercise

Intervention Type DIETARY_SUPPLEMENT

Acute caffeine intake (3 mg/kg) prior each resistance training session of a 8 weeks training program.

Placebo - Females

Group Type PLACEBO_COMPARATOR

Placebo + Resistance exercise

Intervention Type DIETARY_SUPPLEMENT

Acute placeb intake (3 mg/kg of maltodextrin) prior each resistance training session of a 8 weeks training program.

Interventions

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Caffeine + Resistance exercise

Acute caffeine intake (3 mg/kg) prior each resistance training session of a 8 weeks training program.

Intervention Type DIETARY_SUPPLEMENT

Placebo + Resistance exercise

Acute placeb intake (3 mg/kg of maltodextrin) prior each resistance training session of a 8 weeks training program.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age between ≥ 55
* Body mass index (BMI) ≥ 30 kg/m².
* Physically active subjects (\>150 min/week of moderate exercise).
* Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
* Participants capable of performing the tests.

Exclusion Criteria

* History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
* Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
* Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
* Performing strenuous exercise within 48 hours prior to the tests.
* Failing to replicate the same food intake on the two experimental days.
* Consuming caffeine after 6 PM on the day prior to training or testing.
Minimum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Alcala

OTHER

Sponsor Role collaborator

Alberto Pérez-López

OTHER

Sponsor Role lead

Responsible Party

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Alberto Pérez-López

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

Alcalá de Henares, , Spain

Site Status

Countries

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Spain

Other Identifiers

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CEIP/2022/3/055

Identifier Type: -

Identifier Source: org_study_id

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