Role of K+ and Ca2+ in Development of Muscle Fatigue

NCT ID: NCT02712658

Last Updated: 2017-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-03-31

Brief Summary

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The aim of the study is to investigate the role of K+ and Ca2+ in development of muscle fatigue in trained young men.

Detailed Description

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Conditions

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Skeletal Muscle Fatigue in Humans

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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terbutaline

terbutaline is administered by injection (0.25-0.5 mg Bricanyl, AstraZeneca diluted in 9 ml isotonic saline)

Group Type ACTIVE_COMPARATOR

Terbutaline

Intervention Type DRUG

K+ transport and Ca2+ release and uptake function are stimulated by administration of terbutaline

Placebo

placebo is administered as isotonic saline (10 ml)

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Interventions

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Terbutaline

K+ transport and Ca2+ release and uptake function are stimulated by administration of terbutaline

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* physical active healthy men
* aged 18-40 years

Exclusion Criteria

* smokers
* allergy towards terbutaline
* chronic disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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Morten Nielsen

Post.Doc

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Nutrition, Exercise and Sports

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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MIK

Identifier Type: -

Identifier Source: org_study_id

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