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Acute Caffeine Effects on Cardiac Autonomic and Cardiorespiratory Parameters Responses After Aerobic Exercise

NCT ID: NCT02917889

Last Updated: 2016-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Brief Summary

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Check the acute influence of caffeine on the autonomic modulation and cardiorespiratory parameters after aerobic exercise. Hypothesized that caffeine can promote a slower recovery of the cardiorespiratory parameters and the SNA recovery after aerobic exercise.

Detailed Description

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The experimental procedure is divided into three phases, all performed on a treadmill, with a minimum interval of 48 hours between them, in order to allow adequate recovery of the participants. Before the start of the first stage of the experimental protocol or control anthropometric measurements will be carried out, body weight by a digital scale (Plenna, TIN 00139 MAXIMA, Brazil)) and then, using a stadiometer (Plenna, TIN 00139 MAXIMA, Brazil)). The protocols are:

I) Maximum stress test protocol: assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using the Bruce protocol.

II) Control Protocol (PC): at this stage the volunteer will ingest compressed form of placebo similar to Protocol III and remained at rest after 15 minutes in the supine position, followed by 30 minutes of aerobic exercise on a treadmill, 5 minutes with speed 6.0 km / h followed by 25 minutes with 60% of VO2max and the final 60 minutes lying recovery.

III) Experimental protocol (PE): In this stage, the volunteer had performed activities similar to the PC, but will make the tablet intake consists of 300mg of caffeine, a value that is within the maximum daily amount allowed under the FDA.

Conditions

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Autonomic Nervous System Cardiorespiratory Parameters

Keywords

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Caffeine Autonomic Nervous System Recovery Aerobic exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Participants

Study Groups

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Caffeine protocol

300 mg in pills

Group Type EXPERIMENTAL

Caffeine

Intervention Type DRUG

Volunteers will consume 300 mg of caffeine in pills fifteen minutes before treadmill aerobic exercise.

Cardiopulmonary test

Intervention Type OTHER

assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using Buce protocol.

.

Treadmill aerobic exercise

Intervention Type OTHER

30 mim of aerobic exercise (5 minutes at speed of 5.0 km/h for warming-up followed by 25 minutes at 60% of VO2max ).

Placebo protocol

300 mg in pills

Group Type EXPERIMENTAL

Placebo

Intervention Type DRUG

Volunteers will consume 300 mg of placebo in pills fifteen minutes before treadmill aerobic exercise.

Cardiopulmonary test

Intervention Type OTHER

assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using Buce protocol.

.

Treadmill aerobic exercise

Intervention Type OTHER

30 mim of aerobic exercise (5 minutes at speed of 5.0 km/h for warming-up followed by 25 minutes at 60% of VO2max ).

Interventions

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Caffeine

Volunteers will consume 300 mg of caffeine in pills fifteen minutes before treadmill aerobic exercise.

Intervention Type DRUG

Placebo

Volunteers will consume 300 mg of placebo in pills fifteen minutes before treadmill aerobic exercise.

Intervention Type DRUG

Cardiopulmonary test

assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using Buce protocol.

.

Intervention Type OTHER

Treadmill aerobic exercise

30 mim of aerobic exercise (5 minutes at speed of 5.0 km/h for warming-up followed by 25 minutes at 60% of VO2max ).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy men.

Exclusion Criteria

* cardiovascular, orthopedic, respiratory and neurological disorders reported or other pathological conditions that prevent the subject to perform the protocols;
* smokers, alcoholics, or who use drugs that influence the activity of the heart.
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universidade Estadual Paulista Júlio de Mesquita Filho

OTHER

Sponsor Role lead

Responsible Party

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Luana Almeida Gonzaga

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Universidade Estadual Paulista

Presidente Prudente, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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44888015.8.0000.5406

Identifier Type: -

Identifier Source: org_study_id