Correlations Between Fine Manual Motor Skills and Speech Articulation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-13

Study Completion Date

2026-05-01

Brief Summary

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The aim of this study is to examine the relationship between cerebral motor control during a manual task and during an articulary task, using functional MRI in a cohort or young adults aged between 18 and 35.

The literature reveals a well-established relationship between manual motor skills and speech from an anatomical and functional point of view. Some studies indicate a proximity between the motor cortical regions corresponding to the hand and the mouth, with a mutual interaction of the two functions from the earliest stages of life (for example, the Babkin reflex). Experimental data shows that hand movements can be influenced by mouth movements. Neurophysiological studies have demonstrated the existence of a link between these two systems in humans and monkeys.

To date, no study has identified the common cortical networks that are active during these two limb movements in a given sample of subjects. The aim of this study is to determine whether such networks exist. The results could be therapeutically relevant, particularly for stroke patients, by enabling more effective restoration of articulatory abilities through complementary limb movements.

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Detailed Description

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Conditions

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Correlations Between Cerebral Motor Control During a Manual Task and During an Articulatory Task

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Category 2 pilot study involving healthy subjects.

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Motor tasks and oral and facial language

Exercises and MRI

Group Type EXPERIMENTAL

Tasks learning and MRI scan

Intervention Type OTHER

\- 2-week learning and training phase of motor tasks and oral and facial language (OLF) tasks.

Manual fine motor tasks will correspond to activities requiring increasing precision and different types of grip (crushing a ball, modelling clay with the palm of the hand, sorting round coins with thumb/index pliers).

The OLF praxis tasks will correspond to coordinated movements of different parts of the face (cheeks, lips and tongue).

\- MRI (magnetic resonance imaging) exam, During this exam, the investigator will give to the subject instructions for a task to be carried out. These tasks will correspond to the motor tasks previously trained.

Interventions

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Tasks learning and MRI scan

\- 2-week learning and training phase of motor tasks and oral and facial language (OLF) tasks.

Manual fine motor tasks will correspond to activities requiring increasing precision and different types of grip (crushing a ball, modelling clay with the palm of the hand, sorting round coins with thumb/index pliers).

The OLF praxis tasks will correspond to coordinated movements of different parts of the face (cheeks, lips and tongue).

\- MRI (magnetic resonance imaging) exam, During this exam, the investigator will give to the subject instructions for a task to be carried out. These tasks will correspond to the motor tasks previously trained.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Male or female between the ages of 18 and 35
2. Right-handed
3. Member of beneficiary of a social security insurance
4. Signature of an informed consent

Exclusion Criteria

1. Disorders of fine manual motor skills and/or articulatory disorders
2. A neurological history that has affected the subject's cerebral function (stroke, head injury)
3. Contraindication to MRI (presence of ferromagnetic material in the body, claustrophobia)
4. Pregnant women
5. Taking medication that may alter the cerebral haemodynamic signal

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes