Sensorimotor Maps of Vowel Perception and Production

NCT ID: NCT00889317

Last Updated: 2013-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-03-31

Study Completion Date

2012-12-31

Brief Summary

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Speech develops through a co-structuring of auditory and motor representations, especially in the first years of life during language acquisition. In the present study, we will test by means of functional magnetic resonance imaging whether vowel perception and production might depend on a coordination of auditory and motor, articulatory, cortical maps. The outcome of this study will lead to a better understanding of whether both vowel perception and production are processed in the human brain and will provide important insight into brain-language relationships. Besides new theoretical perspectives on speech perception and production, this project might raise important questions concerning patients with speech disorders by identifying which aspects of speech perception and production are functionally linked.

Detailed Description

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The goal of this study is to explore the functional neuroanatomy of vowel processing. To this aim, we will investigate the neural basis of both attentive auditory perception and production of natural French vowels using functional magnetic resonance imaging. More specifically, we will compare vowels that varied along a given phonetic feature dimension while keeping other feature characteristics constant. The phonetic features to be tested are roundedness (rounded/unrounded vowels), place of articulation (front/back vowels) and height (close, close-mid, open-mid vowels). Our study posed three specific questions. First, where exactly in the human brain is the perceptual and motor segregation of different vowel categories accomplished? Second, are these stimulus dimensions implemented topographically in an orthogonal manner, as they vary orthogonally in natural speech? Most specifically, one would expect a topographic segregation between two vowel categories (e.g., front vs back vowels) in both auditory and motor cortices that are characterized by widely distinct acoustic and articulatory values. Third, does these possible sound-related topographic activations in auditory and motor cortices overlap during vowel perception and production? This latter result would support a functional coupling between speech perception and production systems.

Conditions

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Vowel Perception and Production

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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healthy adults

fmri (functional magnetic resonance imaging)

Intervention Type DEVICE

functional image acquisition (75mn) anatomical image acquisition (15mn)

Interventions

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fmri (functional magnetic resonance imaging)

functional image acquisition (75mn) anatomical image acquisition (15mn)

Intervention Type DEVICE

Other Intervention Names

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functional magnetic resonance imaging, sparse sampling

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 60 year-olds
* Personal health insurance

Exclusion Criteria

* Contraindications to IRM (Pacemaker, Aneurysm Clip, Heart/Vascular Clip, Prosthetic Valve, Metal Prosthesis, Claustrophobia, Metal fragments in body).
* Pregnancy / nursing mother
* Participation to another fMRI study in the last month
* Speaking or hearing disorders (past/present)
* Neurological and/or psychiatric disorders (pats/present)
* Left-handed
* Non-native French speaker
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Unité IRM

Principal Investigators

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Marc Sato, PhD

Role: PRINCIPAL_INVESTIGATOR

CNRS GIPSA-LAB UMR 5216

Locations

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IRM 3T - CHU de Grenoble

Grenoble, , France

Site Status

Countries

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France

Other Identifiers

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2008-A01618-47

Identifier Type: REGISTRY

Identifier Source: secondary_id

0824

Identifier Type: -

Identifier Source: org_study_id

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