Memory and Attention in Healthy Children

NCT ID: NCT02858752

Last Updated: 2017-08-09

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 400 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-10-06
• Study Completion Date: 2020-10-06

Brief Summary

This project studies memory and attention in healthy children aged from 5 to 17 years. The processes investigated are short term memory (auditory and visual) and attention.

To characterize these processes involved in childhood, neuropsychological and neurophysiological assessments will be performed (using Electro-encephalography measures, behavioural responses and questionnaires).

Conditions

Healthy Volunteers

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Healthy Children

Memory and Attention in healthy children will be assessed non-invasively through behavioral and electrophysiological measures while participants will perform passive or active computer task involving auditory and/or visual perception.

Group Type: EXPERIMENTAL

Experience 1 : Auditory and Visual Discrimination

Intervention Type: OTHER

Neuropsychological tests consist in listening to sounds in various contexts and providing behavioral responses with response-buttons.

Experience 2 : Passive and Active Auditory Perception

Intervention Type: OTHER

Neuropsychological tests consist in listening to sounds under 2 conditions, an active or a passive one, during which different auditory stimuli will be presented: frequent stimuli (standard) and rare stimuli (deviants). These two stimuli differ in some of their feature (height, duration, …). A third, very rare (novel) stimulus will also be used (the subject's first name). Responses will be provided using a response-button and feedback will be given at each response. EEG will be recorded all along to measure Neurophysiological signals.

Experience 3 : Visual Attention Training

Intervention Type: OTHER

This experience aims at training visual attention through serious games. Children will play against an artificial intelligence and will focus their attention on one out of many possible targets (checkers, cards, boxes) presented on screen. Responses will be provided using a response-button, sometimes completed by an eye-tracking measure. Feedback will be given to the child after his response. EEG will be recorded all along to measure Neurophysiological signals.

Experience 4 : Attention and Distractibility

Intervention Type: OTHER

Neuropsychological tests consist in listening to sounds preceded by a visual cue indicating (or not) in which ear the sounds will be played. The subject Child should detect the target sound (e.g. a dog barking). In some trials, a distracting distraction will be introduced between the visual cue and the target sound. Responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Experience 5 : Sustained Visual Attention

Intervention Type: OTHER

Neuropsychological tests consist in watching visual stimuli presented in 3 blocks of 3 minutes each, with a break of one minute between each block. The child has to detect the presence of a red letter in a pattern made of four letters (the three other letters are black). Behavioral responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Interventions

Experience 1 : Auditory and Visual Discrimination

Neuropsychological tests consist in listening to sounds in various contexts and providing behavioral responses with response-buttons.

Intervention Type: OTHER

Experience 2 : Passive and Active Auditory Perception

Neuropsychological tests consist in listening to sounds under 2 conditions, an active or a passive one, during which different auditory stimuli will be presented: frequent stimuli (standard) and rare stimuli (deviants). These two stimuli differ in some of their feature (height, duration, …). A third, very rare (novel) stimulus will also be used (the subject's first name). Responses will be provided using a response-button and feedback will be given at each response. EEG will be recorded all along to measure Neurophysiological signals.

Intervention Type: OTHER

Experience 3 : Visual Attention Training

This experience aims at training visual attention through serious games. Children will play against an artificial intelligence and will focus their attention on one out of many possible targets (checkers, cards, boxes) presented on screen. Responses will be provided using a response-button, sometimes completed by an eye-tracking measure. Feedback will be given to the child after his response. EEG will be recorded all along to measure Neurophysiological signals.

Intervention Type: OTHER

Experience 4 : Attention and Distractibility

Neuropsychological tests consist in listening to sounds preceded by a visual cue indicating (or not) in which ear the sounds will be played. The subject Child should detect the target sound (e.g. a dog barking). In some trials, a distracting distraction will be introduced between the visual cue and the target sound. Responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Intervention Type: OTHER

Experience 5 : Sustained Visual Attention

Neuropsychological tests consist in watching visual stimuli presented in 3 blocks of 3 minutes each, with a break of one minute between each block. The child has to detect the presence of a red letter in a pattern made of four letters (the three other letters are black). Behavioral responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Normal or corrected vision
• No neurological and psychiatric antecedent.
• No neuro-developmental disorder (dysphasia, dyslexia, dyspraxia, attention deficit disorder…)
• Motivation to participate to the study
• Signed parental informed consent authorizing their child to participate to the study

Exclusion Criteria

• Children educated in a specialized institution.
• Subjects diagnosed with a neurological, psychiatric or neuro-developmental disorder
• Subjects with hearing loss
• Subjects with a visual impairment that cannot be corrected
• Subjects with an organic or chronic disease that can affect cognitive functions.
• Subjects who do not benefit from social security.

• Minimum Eligible Age: 5 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Hospices Civils de Lyon

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Hopital Femme Mère Enfant

Lyon, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Julien JUNG, MD, PhD

Role: CONTACT

julien.jung@inserm.fr

(0)4 27 85 60 53 ext. +33

Facility Contacts

Julia JUNG, MD, PHD

Role: primary

julien.jung@inserm.fr

(0)4 27 85 60 53 ext. +33

Other Identifiers

69HCL15_0711

Identifier Type: -

Identifier Source: org_study_id