Emotional Information Processing in Attention Deficit Disorder With or Without Hyperactivity

NCT ID: NCT03861585

Last Updated: 2020-05-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 54 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-03-15
• Study Completion Date: 2020-03-11

Brief Summary

The aim of this study is to analyse explicit and implicit emotional information processing abilities in children with attention deficit disorder with or without hyperactivity

Detailed Description

The main symptoms of Attentional Deficit Hyperactivity Disorder (ADHD) are inattention, motor agitation and impulsivity. However, other dysfunctions affecting the quality of life remain poorly studied: lack of understanding and management of emotions, focus on the local aspects of a visual scene limiting the ability to assign a general meaning to the scene and alteration of long-term memory encoding. This study aims to analyse these difficulties using different tasks requiring processing of rich and varied everyday images, having high ecological validity. It involves the participation of 56 boys and girls with ADHD, aged 7 to 12 years. A first phase examines the immediate understanding of images using two tasks: semantic categorization (Experiment 1) and emotional evaluation (Experiment 2) of images with positive, negative or neutral emotional valence, and depicting real environments (natural vs. manufactured contexts) or foreground objects pasted into a noise background (inanimate objects vs. animals vs. people. In each trial, one context image and one object image are presented briefly and simultaneously, one in each visual field. In order to be appropriately understood in both their semantic and emotional contents, context images will require more global processing, while object images will require more local, detailed processing. Their semantic (Exp. 1) and emotional (Exp. 2) consistency is manipulated. A week later, the participants have to perform a memory task requiring old/new recognition in a two-alternative forced choice (2AFC) paradigm that presents in each trial a pair of images (one old, one new) having the same emotional valence (Exp. 3). The study will characterize the specificities of processing and representing visual emotional information in ADHD children. The results will be compared with those from a previous study we conducted with the same methodology on neuro-typical children (controls).

Conditions

Attention Deficit Disorder With Hyperactivity; Attention Deficit Disorder Without Hyperactivity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

semantic group

Half of the participants (named the "semantic group") perform a semantic categorisation task.

Group Type: EXPERIMENTAL

Semantic group

Intervention Type: OTHER

The "semantic task" has to categorise semantically (i.e., type of contexts or type of objects) one image at each trial.

emotional group

Half of the participants (named the "emotional group") perform an emotional evaluation task.

Group Type: EXPERIMENTAL

Emotional group

Intervention Type: OTHER

The "emotional task" has to evaluate the emotional content (i.e., neutral, positive or negative) of one image at each trial.

Interventions

Semantic group

The "semantic task" has to categorise semantically (i.e., type of contexts or type of objects) one image at each trial.

Intervention Type: OTHER

Emotional group

The "emotional task" has to evaluate the emotional content (i.e., neutral, positive or negative) of one image at each trial.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Children between 7 and 12 years old…………………………….
• Normal or corrected visual acuity ……………………………….
• ADHD diagnostic given by a doctor according to DSM 5 criteria (Diagnostic and Statistical Manual of Mental Disorders)
• Free from drug treatment until 24 hours before the experiment session……………………….
• Affiliation to a social security system…………………….
• Signature of the authorization documents from one parent or the holder of parental authority

Exclusion Criteria

-History of neurological troubles, dysphasia, autistic spectrum disorder, intellectual disabilities

• Minimum Eligible Age: 7 Years
• Maximum Eligible Age: 12 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Fondation Lenval

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

FOSSOUD Catherine, MD

Role: PRINCIPAL_INVESTIGATOR

Fondation Lenval - Nice Children Hôpitaux Pédiatriques de Nice

Locations

Hôpitaux Pédiatriques de Nice CHU-Lenval

Nice, , France

Countries

France

Other Identifiers

18-HPNCL-07

Identifier Type: -

Identifier Source: org_study_id