Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

NCT ID: NCT05892419

Last Updated: 2023-06-09

Basic Information

• Recruitment Status: ENROLLING_BY_INVITATION
• Total Enrollment: 96 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-07-01
• Study Completion Date: 2026-07-31

Brief Summary

Healthy young adults will view pictures of items while the investigators record electroencephalogram (EEG) brain activity. Then, the investigators will ask the participants to report which items the participants remember seeing. The investigators will examine how the measured brain activity relates to which pictures the participants remember.

Detailed Description

Electrophysiological signatures track distinct subprocesses of working memory, including the number of items and the spatial locations of those items. By identifying how these subprocesses predict long-term memory success in healthy young adults, this project should lead to an intricate understanding of the relationship between working memory and long-term memory. This study will investigate when and how long-term memory failures arise, by using sophisticated machine learning analyses of neural data. Moreover, this study will test the extent to which the investigators can track working memory processes in real time and how the investigators can leverage that information to improve long-term memory success. This will inform basic theories of the relationship between working memory and long-term memory and motivate future applications.

Conditions

Memory; EEG

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: OTHER

Interventions

No intervention

There is no intervention

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• normal or corrected to normal vision

Exclusion Criteria

• non-fluent in English

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Chicago

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Megan deBettencourt

Role: PRINCIPAL_INVESTIGATOR

University of Chicago

Ed Vogel

Role: PRINCIPAL_INVESTIGATOR

University of Chicago

Ed Awh

Role: PRINCIPAL_INVESTIGATOR

University of Chicago

Locations

University of Chicago

Chicago, Illinois, United States

Countries

United States

Other Identifiers

IRB15-1290

Identifier Type: -

Identifier Source: org_study_id