Understanding New Semantic Memory Learnings Across the Lifespan

NCT ID: NCT06442670

Last Updated: 2024-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-30

Study Completion Date

2026-09-30

Brief Summary

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The aim of this research is to specify the changes in brain connectivity (i.e. EEG phase synchronisation between brain regions) associated with semantic learning between individuals belonging to different age groups.

Detailed Description

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Semantic memory is a crucial concept in cognitive science. It has long been conceptualised as a static, amodal memory system containing knowledge about the world, concepts and symbols. Although recourse to this concept is inevitable, the mechanisms, both cognitive and neurobiological, that govern it are far from being elucidated. There are many debates and controversies in this fundamental field of cognitive science, and more specifically around the question of the acquisition and formation of knowledge in semantic memory. The literature on the development of semantic memory during ontogeny is full of contradictions.

A review of this literature highlights the many unanswered questions surrounding semantic memory. How quickly is information encoded and then consolidated into a format that justifies the term semantic knowledge? What are the neural bases underlying the formation of knowledge in semantic memory? How does semantic knowledge evolve through new episodes? How do these mechanisms evolve during ontogeny? To what extent can some semantic learning be preserved from cognitive ageing? In the face of these many questions, the literature highlights the lack of tasks enabling semantic memory to be approached in an operational manner and the need to specify the cerebral mechanisms involved at different ages of life.

The general hypotheses that will be tested as part of the ULIS project are as follows:

1. New semantic learning is possible independently of episodic memory processes.
2. This learning differs according to the age of the participants.

Conditions

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Neurodevelopmental Changes (Childhood, Ageing)

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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6-7 years children

Electroencephalography

Intervention Type DEVICE

Phase synchrony during the completion of the semantic memory task

10-11 years children

Electroencephalography

Intervention Type DEVICE

Phase synchrony during the completion of the semantic memory task

20-35 years adults

Electroencephalography

Intervention Type DEVICE

Phase synchrony during the completion of the semantic memory task

60-70 older adults

Electroencephalography

Intervention Type DEVICE

Phase synchrony during the completion of the semantic memory task

70-80 older adults

Electroencephalography

Intervention Type DEVICE

Phase synchrony during the completion of the semantic memory task

Interventions

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Electroencephalography

Phase synchrony during the completion of the semantic memory task

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Non-opposition by the participant or those exercising parental authority in the case of minors
* French language fluency (assessed by the investigating team)
* Absence of global cognitive deficit attested by a score on the MOCA (Montreal Cognitive Assessment) scale greater than or equal to 26/30 (test carried out at inclusion).

Exclusion Criteria

* Person subject to a guardianship, curatorship or safeguard of justice measure
* Non affiliation to a social security scheme
Minimum Eligible Age

6 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role collaborator

University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clémence Tomadesso

Role: STUDY_CHAIR

University Hospital, Caen

Central Contacts

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Thomas Hinault, PhD

Role: CONTACT

+33231568140

Other Identifiers

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2024-A00167-40

Identifier Type: -

Identifier Source: org_study_id

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