Effect of Transcranial Magnetic Stimulation on Dynamic Cerebral Autoregulation in Healthy Adults
NCT ID: NCT05915923
Last Updated: 2024-02-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
90 participants
INTERVENTIONAL
2023-08-02
2024-04-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Low-frequency rTMS Group
Healthy adults treated with 1Hz repetitive transcranial magnetic stimulation (rTMS)
1 Hz Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received rTMS once a day (stimulation plan: stimulation of M1 region on the dominant hemisphere at 1Hz)
High-frequency rTMS Group
Healthy adults treated with 10Hz repetitive transcranial magnetic stimulation (rTMS)
10 Hz Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received rTMS once a day (stimulation plan: stimulation of M1 region on the dominant hemisphere at 10Hz)
Control group
The Control group received rTMS with sham transcranial magnetic stimulation (sham-rTMS)
Sham Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received sham-rTMS once a day with the same parameters as the 10 Hz rTMS group, but the coil rotated 90° away from the scalp
Interventions
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1 Hz Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received rTMS once a day (stimulation plan: stimulation of M1 region on the dominant hemisphere at 1Hz)
10 Hz Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received rTMS once a day (stimulation plan: stimulation of M1 region on the dominant hemisphere at 10Hz)
Sham Repetitive transcranial magnetic stimulation
After enrollment, healthy adults received sham-rTMS once a day with the same parameters as the 10 Hz rTMS group, but the coil rotated 90° away from the scalp
Eligibility Criteria
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Inclusion Criteria
2. Willing to participate and sign the informed consent；
3. Bilateral temporal windows were well penetrated;
Exclusion Criteria
2. Suffering from infectious diseases in late one month;
3. Pregnancy or breast-feeding;
4. Sleep disorders, anxiety and depression,
5. Alcohol or drug abuse;
6. History of prescription drugs or over-the-counter (OTC) drugs in the past 2 weeks;
7. History of epilepsy or family history of epilepsy;
8. Implants ( stents or metals );
9. Other conditions that the researchers think are not suitable for the project.
18 Years
59 Years
ALL
Yes
Sponsors
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Yi Yang
OTHER
Responsible Party
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Yi Yang
Vice President of First Hospital of Jilin University
Locations
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The First Hospital of Jilin University
Jilin, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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TMSCA-HA
Identifier Type: -
Identifier Source: org_study_id
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