Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
25 participants
INTERVENTIONAL
2015-07-23
2015-12-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Healthy volunteers
Healthy volunteers
Magnetic Resonance Imaging during intern speech, listening, talking, thinking.
MRI
Interventions
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Healthy volunteers
Magnetic Resonance Imaging during intern speech, listening, talking, thinking.
MRI
Eligibility Criteria
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Inclusion Criteria
* Right-handed
* French as mother tongue
* Visual acuity that allow to read stimulis (contact lens authorized)
* Healthy subject
Exclusion Criteria
* Claustrophobia
18 Years
65 Years
ALL
Yes
Sponsors
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University Hospital, Grenoble
OTHER
Responsible Party
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Principal Investigators
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Alexandre Krainik, Professor
Role: PRINCIPAL_INVESTIGATOR
Grenoble Hospital University
Locations
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UniversityHospitalGrenoble
La Tronche, , France
Countries
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References
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Baciu MV, Rubin C, Decorps MA, Segebarth CM. fMRI assessment of hemispheric language dominance using a simple inner speech paradigm. NMR Biomed. 1999 Aug;12(5):293-8. doi: 10.1002/(sici)1099-1492(199908)12:53.0.co;2-6.
Basho S, Palmer ED, Rubio MA, Wulfeck B, Muller RA. Effects of generation mode in fMRI adaptations of semantic fluency: paced production and overt speech. Neuropsychologia. 2007 Apr 9;45(8):1697-706. doi: 10.1016/j.neuropsychologia.2007.01.007. Epub 2007 Jan 16.
Bookheimer SY, Zeffiro TA, Blaxton T, Gaillard W, Theodore W. Regional cerebral blood flow during object naming and word reading. Human Brain Mapping. 1995;3:93-106.
Clark A, Karmiloff-Smith A. The cognizer's innards: a psychological and philosophical perspective on the development of thought. Mind & Language. 1993;8:487-519.
Conrad B, Schonle P. Speech and respiration. Arch Psychiatr Nervenkr (1970). 1979 Apr 12;226(4):251-68. doi: 10.1007/BF00342238.
Davis RN, Nolen-Hoeksema S. Cognitive inflexibility among ruminators and nonruminators. Cognitive Therapy and Research. 2000;24:699-711.
Frings M, Dimitrova A, Schorn CF, Elles HG, Hein-Kropp C, Gizewski ER, Diener HC, Timmann D. Cerebellar involvement in verb generation: an fMRI study. Neurosci Lett. 2006 Nov 27;409(1):19-23. doi: 10.1016/j.neulet.2006.08.058. Epub 2006 Oct 12.
Huang J, Carr TH, Cao Y. Comparing cortical activations for silent and overt speech using event-related fMRI. Hum Brain Mapp. 2002 Jan;15(1):39-53. doi: 10.1002/hbm.1060.
Lupyan G. Extracommunicative functions of language: verbal interference causes selective categorization impairments. Psychon Bull Rev. 2009 Aug;16(4):711-8. doi: 10.3758/PBR.16.4.711.
McGuire PK, Silbersweig DA, Murray RM, David AS, Frackowiak RS, Frith CD. Functional anatomy of inner speech and auditory verbal imagery. Psychol Med. 1996 Jan;26(1):29-38. doi: 10.1017/s0033291700033699.
Morin A. Inner Speech Encyclopedia of Human Behavior. 2012;Elsevier:436-43.
Netsell R, Ashley E, Bakker K. The Inner Speech of Persons who Stutter. Proceedings of the International Motor Speech Conference. Savannah, Georgia2010
Olivers CN, Nieuwenhuis S. The beneficial effects of additional task load, positive affect, and instruction on the attentional blink. J Exp Psychol Hum Percept Perform. 2006 Apr;32(2):364-79. doi: 10.1037/0096-1523.32.2.364.
Owen WJ, Borowsky R, Sarty GE. FMRI of two measures of phonological processing in visual word recognition: ecological validity matters. Brain Lang. 2004 Jul-Sep;90(1-3):40-6. doi: 10.1016/S0093-934X(03)00418-8.
Palmer ED, Rosen HJ, Ojemann JG, Buckner RL, Kelley WM, Petersen SE. An event-related fMRI study of overt and covert word stem completion. Neuroimage. 2001 Jul;14(1 Pt 1):182-93. doi: 10.1006/nimg.2001.0779.
Partovi S, Konrad F, Karimi S, Rengier F, Lyo JK, Zipp L, Nennig E, Stippich C. Effects of covert and overt paradigms in clinical language fMRI. Acad Radiol. 2012 May;19(5):518-25. doi: 10.1016/j.acra.2011.12.017. Epub 2012 Jan 27.
Rosen HJ, Ojemann JG, Ollinger JM, Petersen SE. Comparison of brain activation during word retrieval done silently and aloud using fMRI. Brain Cogn. 2000 Mar;42(2):201-17. doi: 10.1006/brcg.1999.1100.
Shergill SS, Bullmore ET, Brammer MJ, Williams SC, Murray RM, McGuire PK. A functional study of auditory verbal imagery. Psychol Med. 2001 Feb;31(2):241-53. doi: 10.1017/s003329170100335x.
Shuster LI, Lemieux SK. An fMRI investigation of covertly and overtly produced mono- and multisyllabic words. Brain Lang. 2005 Apr;93(1):20-31. doi: 10.1016/j.bandl.2004.07.007.
Uttl B, Morin A, Faulds TJ, Hall T, Wilson JM. Sampling Inner Speech Using Text Messaging. Proceedings of the Canadian Society for Brain, Behavior, and Cognitive Science. Kingston2012. p. 287.
Roger E, Rodrigues De Almeida L, Loevenbruck H, Perrone-Bertolotti M, Cousin E, Schwartz JL, Perrier P, Dohen M, Vilain A, Baraduc P, Achard S, Baciu M. Unraveling the functional attributes of the language connectome: crucial subnetworks, flexibility and variability. Neuroimage. 2022 Nov;263:119672. doi: 10.1016/j.neuroimage.2022.119672. Epub 2022 Oct 6.
Other Identifiers
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38RC14.304
Identifier Type: -
Identifier Source: org_study_id
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