Pre-exercise Ingestion of a Low Glycaemic Index Rice-based Mixed Meal Increases Fat Oxidation and Endurance Running in a Hot-humid Environment

NCT ID: NCT06544252

Last Updated: 2024-08-09

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 12 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-01-01
• Study Completion Date: 2023-01-30

Brief Summary

The objective of this research is to determine the influence of low and high glycemic index Malaysian pre-exercise mixed meals on endurance exercise performance in a hot-humid environment. Glycemic index (GI) is a method used to classify CHO-containing foods based on their influence on postprandial blood glucose when compared to the response on blood glucose after ingesting the same amount of CHO from a reference food (glucose or bread). Low GI (LGI) foods are digested and absorbed more slowly as compared to high GI (HGI) foods, resulting in a stable rise in blood glucose levels.

The participants were trained male endurance long-distance runners. On the day of experimental trials, they consumed pre-exercise rice-based mixed meal, either LGI or HGI 3 hours before endurance running exercise. After that, they ran for 45 minutes at constant running speed equivalent to 70% VO2peak, followed by 10km time-trial. The respiratory gases, blood measures, rectal and skin temperature were measured throughout the running test.

Conditions

Healthy; Trained Athletes

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Low glycaemic index, Then high glycaemic index

The participants were randomised to receive pre-exercise low glycaemic index rice-based mixed meal followed by a cross-over with the high glycaemic index rice-based mixed meal after one week

Group Type: EXPERIMENTAL

Low glycaemic index rice-based mixed meal (GI value = 47)

Intervention Type: DIETARY_SUPPLEMENT

The mixed meal consisted of Basmati rice, chicken, and green-leafy vegetables. The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

High glycaemic index rice-based mixed meal (GI value = 80)

Intervention Type: DIETARY_SUPPLEMENT

The mixed meal consisted of fragrant rice, chicken, and green-leafy vegetables.The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

High glycaemic index, Then low glycaemic index

The participants were randomised to receive pre-exercise high glycaemic index rice-based mixed meal followed by a cross-over with the low glycaemic index rice-based mixed meal after one week

Group Type: EXPERIMENTAL

Low glycaemic index rice-based mixed meal (GI value = 47)

Intervention Type: DIETARY_SUPPLEMENT

The mixed meal consisted of Basmati rice, chicken, and green-leafy vegetables. The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

High glycaemic index rice-based mixed meal (GI value = 80)

Intervention Type: DIETARY_SUPPLEMENT

The mixed meal consisted of fragrant rice, chicken, and green-leafy vegetables.The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

Interventions

Low glycaemic index rice-based mixed meal (GI value = 47)

The mixed meal consisted of Basmati rice, chicken, and green-leafy vegetables. The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

Intervention Type: DIETARY_SUPPLEMENT

High glycaemic index rice-based mixed meal (GI value = 80)

The mixed meal consisted of fragrant rice, chicken, and green-leafy vegetables.The energy content of the mixed meal was based on the body mass of the participant. The amount of CHO was 1.3 g.kg-1 body mass (Burke et al. 2019), and the amount of protein given was 0.5 g.kg-1 per meal (Witard, Garthe and Phillips 2019).

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• healthy
• age 18-35 years old
• trained (peak oxygen consumption (V̇O2peak): ≥ 55 mL.kg-1.min-1)
• training volume (>150 min, ≥ three times per week)
• competing at the national level
• >2-year of running experience
• tier 2 (trained) or tier 3 (highly trained) runners (McKay et al. 2022)
• no allergies to any test foods

Exclusion Criteria

• diagnosis of chronic diseases (i.e. diabetes mellitus, hypertension, cardiovascular disease)
• bone, muscle or joint impairments
• on medication
• currently smoking
• use of illicit drugs
• use of dietary supplements
• on any particular diet

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Universiti Sains Malaysia

OTHER

Sponsor Role: lead

Responsible Party

Zaini Bahari

Principle Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ahmad Munir Che Muhamed, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Community Health, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia

Locations

Department of Community Health, Advanced Medical and Dental Institute

Kepala Batas, Pulau Pinang, Malaysia

Countries

Malaysia

Other Identifiers

USM/JEPeM/19010083

Identifier Type: -

Identifier Source: org_study_id