The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement

NCT ID: NCT06520761

Last Updated: 2024-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-01

Study Completion Date

2024-12-01

Brief Summary

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The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine

Detailed Description

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the study involves two groups the first group received low level laser at the upper right canine, while the upper left canine act as a control. The second group received injectable platelet rich fibrin at the upper right canine, while the upper left canine act as a control. in each group we will compare rate of canine retraction between both sides, and amount of root resorption also we will compare both groups regarding rate of canine retraction and amount of root resorption

Conditions

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Rate of Canine Retraction Root Resorption

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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injectable platelet rich fibrin

blood sample is collected from the patient, centrifuged at 700rpm for 3 minutes then the resulted injectable platelet rich fibrin is injected around the upper right canine while the upper left canine act as a control

Group Type EXPERIMENTAL

Injectable platelet rich fibrin

Intervention Type PROCEDURE

blood sample obtained from the participant, centrifuged at 700 rpm to produce injectable platelet rich fibrin, this will be injected around the upper canine

Low Level LASER

low level laser from diode laser machine is applied around the upper right canine and the upper left canine acts as a control

Group Type EXPERIMENTAL

Low Level LASER

Intervention Type DEVICE

Diode LASER device is used to apply Low Level LASER around the upper canine

Interventions

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Injectable platelet rich fibrin

blood sample obtained from the participant, centrifuged at 700 rpm to produce injectable platelet rich fibrin, this will be injected around the upper canine

Intervention Type PROCEDURE

Low Level LASER

Diode LASER device is used to apply Low Level LASER around the upper canine

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patients with age 18 years or older.
2. Presence of all permanent teeth except for the third molar.
3. Presence of malocclusion requiring maxillary first premolar extraction such as (class II division 1 or bimaxillary dentoalveolar protrusion).

Exclusion Criteria

1. Patient with a history of previous orthodontic treatment.
2. Medical problems may interfere with orthodontic treatment.
3. Bad oral hygiene.
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Faculty of Dental Medicine for Girls

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Samir A Ebrahim, Professor

Role: PRINCIPAL_INVESTIGATOR

Head of orthodontic department at faculty of Dental Medicine for Girls Al-Azhar university

Locations

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Faculty of Dental Medicine for Girls Al Azhar university

Cairo, Naser City, Egypt

Site Status

Countries

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Egypt

References

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Zeitounlouian TS, Zeno KG, Brad BA, Haddad RA. Effect of injectable platelet-rich fibrin (i-PRF) in accelerating orthodontic tooth movement : A randomized split-mouth-controlled trial. J Orofac Orthop. 2021 Jul;82(4):268-277. doi: 10.1007/s00056-020-00275-x. Epub 2021 Jan 22.

Reference Type BACKGROUND
PMID: 33481053 (View on PubMed)

Related Links

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https://pubmed.ncbi.nlm.nih.gov/33481053/

The role of platelet-rich fibrin (PRF) in accelerating orthodontic tooth movement has been controversially discussed in available clinical studies. Objective: To investigate the effectiveness of i-PRF in accelerating maxillary canine retraction.

Other Identifiers

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ORTHO-108-5-b

Identifier Type: -

Identifier Source: org_study_id

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