Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
NCT ID: NCT06302296
Last Updated: 2025-09-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
14 participants
INTERVENTIONAL
2025-12-20
2026-07-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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injectable form of PRF
A group of patients in which participants will be undergo to orthodontic treatment will be received a 0.9 ml injection of PRF after 1st premolar extraction.
injectable form of PRF
A group of patients in which participants will be undergo to orthodontic treatment will be received a 0.9 ml injection of PRF after 1st premolar extraction.
traditional orthodontic treatment
A group of patients in which participants will be undergo to traditional orthodontic treatment will be received a Placebo injection after 1st premolar extraction.
Placebo injection
A group of patients in which participants will be undergo to traditional orthodontic treatment will be received a Placebo injection after 1st premolar extraction.
Interventions
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injectable form of PRF
A group of patients in which participants will be undergo to orthodontic treatment will be received a 0.9 ml injection of PRF after 1st premolar extraction.
Placebo injection
A group of patients in which participants will be undergo to traditional orthodontic treatment will be received a Placebo injection after 1st premolar extraction.
Eligibility Criteria
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Inclusion Criteria
* Class I or Class II malocclusion, first model according to Angle, with skeletal class I or II and a normal or mild vertical growth pattern.
* All permanent upper teeth, up to the first molar, are present, with the possibility of attaching brackets to all teeth in a correct position.
* The patient has good oral health.
Exclusion Criteria
* Severe malalignment of one of the teeth (palatal quadrant, ectopic canine, ectopic premolar).
* The patient has undergone previous orthodontic treatment.
* The patient is subject to any drug treatment that may affect orthodontic dental movement (cortisone, non-steroidal anti-inflammatory drugs).
* The patient has poor oral health.
* Commitment to periodic follow-up appointments.
18 Years
26 Years
ALL
No
Sponsors
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Hama University
OTHER
Responsible Party
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FADI JNAID
Syria-Hama University
Principal Investigators
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Eisa Salami, MSc student
Role: PRINCIPAL_INVESTIGATOR
Hama University
Rabab Alsabbagh, Professor
Role: STUDY_CHAIR
Hama University
Locations
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Fadi Jnaid
Hama, , Syria
Countries
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Central Contacts
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Facility Contacts
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Role: backup
Other Identifiers
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Hama University/
Identifier Type: -
Identifier Source: org_study_id
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