Evaluation of Different Orthodontic Tooth Movements Assisted With Injectable Platelet Rich Fibrin

NCT ID: NCT05616936

Last Updated: 2022-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1/PHASE2

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-04-01

Brief Summary

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The present prospective clinical study will be undertaken for assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization\& intrusion of anterior teeth in deep bite cases

Detailed Description

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Assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization\& intrusion of anterior teeth in deep bite cases

Conditions

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Effect of Platelet Rich Fibrin With Different Tooth Movements

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Factorial Assignment
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Group I

Intervention side: application of i-PRF with distalization of maxillary first molar that will be performed on intervention sides according to a standardized protocol.

Group Type EXPERIMENTAL

injectable platelet rich fibrin

Intervention Type BIOLOGICAL

injectable platelet rich fibrin

Group II

Control side: distalization of maxillary first molar that will be performed without any intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Group A

levelling and alignment assisted with Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol.

Group Type EXPERIMENTAL

injectable platelet rich fibrin

Intervention Type BIOLOGICAL

injectable platelet rich fibrin

Group B

leveling and alignment will be commenced without Injection of Injectable platelet-rich fibrin (i-PRF)

Group Type NO_INTERVENTION

No interventions assigned to this group

Group a

Will includes 9 patients who will receive intrusive arch after leveling and alignment assisted Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol.

Group Type EXPERIMENTAL

injectable platelet rich fibrin

Intervention Type BIOLOGICAL

injectable platelet rich fibrin

Group b

Will includes 9 patients who will receive intrusive utility arches after leveling and alignment without Injection of Injectable platelet-rich fibrin (i-PRF)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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injectable platelet rich fibrin

injectable platelet rich fibrin

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

All permanent teeth present, 3rd molars are excluded. Good oral and general health. No systemic disease/medication that could interfere with orthodontic tooth movement. No previous orthodontic treatment.

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Exclusion Criteria

Poor oral hygiene or periodontally compromised patient. Patient with craniofacial anomalies or previous history of trauma, bruxism or parafunctions.

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Minimum Eligible Age

15 Years

Maximum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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farouk ahmed hussein

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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AlAzhar university

Cairo, , Egypt

Site Status

Countries

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Egypt

References

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Zeitounlouian TS, Zeno KG, Brad BA, Haddad RA. Effect of injectable platelet-rich fibrin (i-PRF) in accelerating orthodontic tooth movement : A randomized split-mouth-controlled trial. J Orofac Orthop. 2021 Jul;82(4):268-277. doi: 10.1007/s00056-020-00275-x. Epub 2021 Jan 22.

Reference Type BACKGROUND
PMID: 33481053 (View on PubMed)

Erdur EA, Karakasli K, Oncu E, Ozturk B, Hakki S. Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement. Angle Orthod. 2021 May 1;91(3):285-292. doi: 10.2319/060320-508.1.

Reference Type BACKGROUND
PMID: 33459765 (View on PubMed)

Other Identifiers

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837/140

Identifier Type: -

Identifier Source: org_study_id

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