Treatment of Class III Malocclusion Using Modified Fixed Mandibular Retractor Appliance

NCT ID: NCT03354442

Last Updated: 2019-07-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-15

Study Completion Date

2019-01-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This experimental study aims to evaluate the efficiency of the Modified Fixed Mandibular Retractor Appliance in the treatment of skeletal class III malocclusion.

The study sample will consist of 44 patients with skeletal class III malocclusion. The sample will be allocated randomly into two groups: experimental group and untreated control group.

The soft and hard tissue changes will be assessed using lateral cephalometric radiographs before the treatment and after obtaining 3mm positive overjet.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This research aimes to evaluate the effects of a Class III functional appliance \[the modified fixed mandibular retractor (MFMR)\] in the early treatment of skeletal Class III deformities.

It was not ethical to expose all candidate children to radiographic examination. Therefore, the assessment of skeletal Class III malocclusion was based on clinical judgment. Each patient was examined, while his/her mandible was kept at its retruded contact position to evaluate both jaws in space. Those who met the inclusion criteria were then sent to the radiographic department.

The radiographic lateral cephalograms were obtained in the patients' habitual occlusion.

All patients in the treatment group were treated by one specialist orthodontist 'AA' using the MFMR. The appliance consisted of the following elements: (1) Two acrylic upper posterior bite planes which cover the deciduous and permanent molars ( 2) Two transpalatal arch (0.8-mm TMA) with opposite U loop, the anterior one is near the first deciduous molars while the posterior one is near the first permanent molars (3) upper reversed labial bow (0.9-mm stainless steel) extending to the cervical edges of the mandibular anterior teeth from the labial surface of the lower primary canine on one side to the other labial surface of the contralateral tooth. This bow will be activated to hold the mandible in its maximum posterior physiologic position; and (4) the anterior spring (0.8-mm TMA) which starts from the acrylic bite plane in both sides, makes loop, then bends to touch the cingulum of upper incisors to procline the upper permanent incisors when diagnosed as retroclined.

The untreated group will receive no orthodontic treatment during the observation period. According to the Dental School Local Research Ethics Committee's guidelines, all children in the untreated group will receive orthodontic treatment after the end of the observational period of the study at no cost.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Malocclusion, Angle Class III

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
A person who is not related to the research will paste a piece of paper over the Patient's name and the date of the photo then will give each x-ray a code and blind these codes on the researcher during the assessing process.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Modified Fixed Mandibular Retractor

All patients in this group will be treated using Modified Fixed Mandibular Retractor Appliance. This appliance will be used full-time.

Group Type EXPERIMENTAL

Modified Fixed Mandibular Retractor Appliance

Intervention Type DEVICE

All patients with Class III malocclusion will be treated using the Modified Fixed Mandibular Retractor Appliance

Untreated control group

All patients in this group will be observed during the period of treating the patients in the other group to assess the growth changes.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Modified Fixed Mandibular Retractor Appliance

All patients with Class III malocclusion will be treated using the Modified Fixed Mandibular Retractor Appliance

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients in early mixed dentation (7-9 years old).
* Skeletal class III caused by mandibular prognathism with or without maxillary deficiency judged clinically and confirmed radiographically (ANB≤1).
* Anterior crossbite on two teeth or more.
* Normal inclination of the lower incisors with the mandibular plane.
* Good oral hygiene.

Exclusion Criteria

* Poor oral hygiene.
* Previous orthodontic treatment.
* Patients with syndromes, clefts, or craniofacial abnormalities.
* Severe skeletal class III resulting primarily from mandibular prognathism (ANB less than - 4 with no functional shift on closure)
* Patients with facial asymmetry.
* Patients with vertical growth pattern.
Minimum Eligible Age

7 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Damascus University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ahmad S Burhan, PhD.

Role: STUDY_CHAIR

Department of Orthodontics, Faculty of Dentistry, Damascus University, Damascus, Syria

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Damascus University

Damascus, , Syria

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Syria

References

Explore related publications, articles, or registry entries linked to this study.

Alhaija ES. Skeletal, dental and soft tissue changes in postural class III malocclusion treated with a maxillary removable appliance. J Clin Pediatr Dent. 2006 Winter;31(2):149-52. doi: 10.17796/jcpd.31.2.u286433up81kt472.

Reference Type BACKGROUND
PMID: 17315814 (View on PubMed)

Akin M, Ucar FI, Chousein C, Sari Z. Effects of chincup or facemask therapies on the orofacial airway and hyoid position in Class III subjects. J Orofac Orthop. 2015 Nov;76(6):520-30. doi: 10.1007/s00056-015-0315-3.

Reference Type BACKGROUND
PMID: 26446505 (View on PubMed)

Majanni AM, Hajeer MY. The Removable Mandibular Retractor vs the Bone-anchored Intermaxillary Traction in the Correction of skeletal class III Malocclusion in children: A Randomized Controlled Trial. J Contemp Dent Pract. 2016 May 1;17(5):361-71. doi: 10.5005/jp-journals-10024-1856.

Reference Type BACKGROUND
PMID: 27443361 (View on PubMed)

Seehra J, Fleming PS, Mandall N, Dibiase AT. A comparison of two different techniques for early correction of Class III malocclusion. Angle Orthod. 2012 Jan;82(1):96-101. doi: 10.2319/032011-197.1. Epub 2011 Aug 1.

Reference Type BACKGROUND
PMID: 21806467 (View on PubMed)

Atalay Z, Tortop T. Dentofacial effects of a modified tandem traction bow appliance. Eur J Orthod. 2010 Dec;32(6):655-61. doi: 10.1093/ejo/cjp153. Epub 2010 Mar 26.

Reference Type BACKGROUND
PMID: 20348164 (View on PubMed)

Kapur A, Chawla HS, Utreja A, Goyal A. Early class III occlusal tendency in children and its selective management. J Indian Soc Pedod Prev Dent. 2008 Sep;26(3):107-13. doi: 10.4103/0970-4388.43191.

Reference Type BACKGROUND
PMID: 18923222 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

UDDS-Ortho-08-2017

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.