Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

129 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-09-30

Brief Summary

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The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions. The main question\[s\] it aims to answer are:

In the perspective of improvement in pain and healing;

* Does A-PRF performs better than control group?
* Does Bone-wax performs better than control group?
* Healing index and Pain scale score Comparison of A-PRF and Bone-wax; if one is better than the other? Participants will be asked to give resoponse to a post-operative symptom severiety (PoSSe) scale. An investigator will score the patient's extraction for hemostasis and on healing index \[describe the main tasks participants will be asked to do, treatments they'll be given and use bullets if it is more than 2 items\]. If there is a comparison group: Researchers will compare \[insert groups\] to see if \[insert effects\].

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Detailed Description

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Conditions

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Post-Extraction Socket Hemostasis Post-Extraction Socket Pain Relief Post-Extraction Socket Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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A-PRF

Advance Platelet-Rich Fibrin

Group Type EXPERIMENTAL

A-PRF

Intervention Type BIOLOGICAL

0.5 to 1g of Advance Platelet-Rich Fibrin (A-PRF) clot for each dental socket.

Bone-wax

Group Type ACTIVE_COMPARATOR

Bone-wax

Intervention Type COMBINATION_PRODUCT

0.5 to 1g of Bone-wax for each dental socket

Conventional Dental Extraction protocol

Control Group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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A-PRF

0.5 to 1g of Advance Platelet-Rich Fibrin (A-PRF) clot for each dental socket.

Intervention Type BIOLOGICAL

Bone-wax

0.5 to 1g of Bone-wax for each dental socket

Intervention Type COMBINATION_PRODUCT

Other Intervention Names

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combination of beeswax and other products

Eligibility Criteria

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Inclusion Criteria

* All patients who need extraction of mandibular posterior teeth
* Overall, systemically healthy individuals (Established based on history, i.e., patients who do not take medicine for any systemic condition).
* INR within normal range.

Exclusion Criteria

* Patients with a diagnosed systemic condition.
* Patients who are immunocompromised.
* Patients who are unwilling to participate or withdraw from the study.
* Patients who fail to report on the seventh and twenty-first post-extraction day.
* Patients with physical or mental impairments who need assistance in taking their medications.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes