Use of PRF in Treatment of Dry Socket.

NCT ID: NCT04476121

Last Updated: 2021-04-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2021-07-01

Brief Summary

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The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.

Detailed Description

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The main objective was to compare the effects of using two different methods in the treatment of dry socket (alveolar osteitis), which is a postoperative complication of dental extraction. The first was Nipas, applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth and reoccurrence of dry socket, patients were treated with application of PRF.

Conditions

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Alveolar Osteitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The first medicine was applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth in the same patient and reoccurrence of dry socket, patients were treated with PRF application.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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PRF application

Patients with alveolar osteitis in which PRF application was performed.

Group Type EXPERIMENTAL

PRF application

Intervention Type PROCEDURE

PRF application into post-operative wound.

Aspirin application

Patients with alveolar osteitis in which Nipas was used.

Group Type ACTIVE_COMPARATOR

Nipas application

Intervention Type DRUG

Nipas application into post-operative wound.

Interventions

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PRF application

PRF application into post-operative wound.

Intervention Type PROCEDURE

Nipas application

Nipas application into post-operative wound.

Intervention Type DRUG

Other Intervention Names

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Aspirin paste

Eligibility Criteria

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Inclusion Criteria

* no known medical history of abnormal platelet counts,
* patients with symmetric teeth qualified for extraction,

Exclusion Criteria

* patients treated previously for existing dry socket,
* patients allergic to acetylsalicylic acid ,
* systemic diseases,
* pregnancy,
* lactation,
* drugs known to affect the number or function of platelets,
* abnormal platelet counts,
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medical University of Lodz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anna Janas-Naze, Prof.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Lodz

Locations

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Department of Oral Surgery

Lodz, , Poland

Site Status

Countries

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Poland

Other Identifiers

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0002

Identifier Type: -

Identifier Source: org_study_id

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