Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
NCT ID: NCT04374214
Last Updated: 2020-05-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
56 participants
INTERVENTIONAL
2018-12-01
2020-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Complete Pulpotomy using mineral trioxide aggregate
Twenty-eight patients with curiously exposed permanent molars will be treated with complete pulpotomy by using Mineral Trioxide Aggregate.
Complete Pulpotomy using Mineral Trioxide Aggregate
Inflammed coronal pulp tissue will be removed till the canal orifices and mineral trioxide aggregate placed over the amputated pulp stump.
Complete Pulpotomy using Simvastatin-alphatricalcium phosphate
Twenty-eight patients with curiously exposed permanent molars will be treated with complete pulpotomy by using Simvastatin -alphatricalcium phospahte.
Complete Pulpotomy using Simvastain -alphatricalcium phosphate
Inflammed coronal pulp tissue will be removed till the canal orifices and Simvastatin -alpha tricalcium phosphate placed over the amputated pulp stump.
Interventions
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Complete Pulpotomy using Mineral Trioxide Aggregate
Inflammed coronal pulp tissue will be removed till the canal orifices and mineral trioxide aggregate placed over the amputated pulp stump.
Complete Pulpotomy using Simvastain -alphatricalcium phosphate
Inflammed coronal pulp tissue will be removed till the canal orifices and Simvastatin -alpha tricalcium phosphate placed over the amputated pulp stump.
Eligibility Criteria
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Inclusion Criteria
2. Age group of 15 to 40 years
3. Mature permanent mandibular molars with reversible pulpitis (positive response on the cold test and early response as compared to the adjacent or contralateral tooth)
4. Teeth exhibiting occlusal pulp exposure from primary dental caries.
5. Absence of periapical lesions assessed by radiographic examination.
6. Tooth demonstrating no mobility or swelling and no tenderness to percussion or palpation
Exclusion Criteria
2. Teeth with irreversible pulpitis (spontaneous pain) or pulp necrosis, chronic periodontitis, cracked tooth, internal or external resorption, calcified canals, associated with sinus tract and furcation or apical radiolucency.
3. Immune-compromised, pregnant and patients with any systemic disorder.
4. Patients taking statin medication.
5. Failure to obtain authorization from the patient.
15 Years
40 Years
ALL
Yes
Sponsors
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Postgraduate Institute of Dental Sciences Rohtak
OTHER
Responsible Party
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Principal Investigators
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Sudeepender Gehlot
Role: PRINCIPAL_INVESTIGATOR
PGIDS, Rohtak
Locations
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PGIDS
Rohtak, Haryana, India
Countries
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Other Identifiers
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Dr Sudeepender Gehlot
Identifier Type: -
Identifier Source: org_study_id
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