Regenerative Endodontics in Mature Permanent Teeth

NCT ID: NCT05892536

Last Updated: 2023-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-05

Study Completion Date

2022-01-30

Brief Summary

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this study was designed to compare the clinical and radiographic success of REPs after using blood clot scaffold in non-vital mature permanent teeth with or without photobiomodultion therapy

Detailed Description

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Conditions

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Regenerative Endodontics

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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blood clot regeneration

the regenerative procedures were performed by over-instrumentation the apices and irritating the apical tissues to induce bleeding into the root canal, then orifices plugged with MTA over blood clot and restored with GI.

Group Type EXPERIMENTAL

dental regenerative endodontics

Intervention Type PROCEDURE

regenerative procedures performed in necrotic mature permanent teeth

photo-biomodulation regeneration

photobiomodulation therapy was carried out using diode laser with wavelenght 810 nm and output power 300 mW on the apical root areas of buccal and lingual surfaces at 48 hours intervals for 2 weeks after completion of the regenerative procedures which were performed by over-instrumentation the apices and irritating the apical tissues to induce bleeding into the root canal, then orifices plugged with MTA over blood clot and restored with GI.

Group Type ACTIVE_COMPARATOR

dental regenerative endodontics

Intervention Type PROCEDURE

regenerative procedures performed in necrotic mature permanent teeth

Interventions

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dental regenerative endodontics

regenerative procedures performed in necrotic mature permanent teeth

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients free from any systemic diseases or genetic disorders.
* Children aged 9-13 years old of both sexes.
* Traumatically or cariously exposed single rooted mature permanent teeth which may be asymptomatic or manifested with dull ache pain, or spontaneous unprovoked toothache.
* Non-vital single rooted mature permanent teeth that indicated for endodontic treatment
* Swelling close to involved tooth accompanied with or without fistula.
* Negative response to cold \& electrical pulp test.
* Informed Consent.

Exclusion Criteria

* Unrestorable teeth, or that need post and core for the final restoration.
* Immature permanent teeth.
* Known allergy, sensitivity to ciprofloxacin, metronidazol.
* Uncooperativeness of child and/or parents or caregiver's behavior.
* Presence of calcific metamorphosis inside root canals.
Minimum Eligible Age

9 Years

Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Salma fathy

OTHER

Sponsor Role lead

Responsible Party

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Salma fathy

Doctor of pedodontics

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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salma khattab, master

Role: PRINCIPAL_INVESTIGATOR

Minia University

Locations

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Minia University

Minya, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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364

Identifier Type: -

Identifier Source: org_study_id

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