Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
NCT ID: NCT03350841
Last Updated: 2017-12-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
36 participants
INTERVENTIONAL
2018-01-31
2019-12-31
Brief Summary
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Detailed Description
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in the second visit, removal of intracanal medication then obturaton of the canals in the control group. while in the intervention group,over instrumentation of the canals beyond the working length using k-file size 20-35 to establish bleeding in the canals.then blood sample is collected for PRP preparation then injected into the canal.the patient will record post operative pain 6,12,24,48 hours then 3,4,5 days later.then they will do CBCT at 6, 12 months after the treatment to assess peri-apical healing
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Revascularization
platelet rich plasma injected in the canals
Platelet rich plasma PRP
blood sample is collected to prepare platelet rich plasma injected in the canal
root canal treatment
endodontic treatment obturated with gutta percha
root canal treatment
conventional root canal treatment and obturation with guttapercha
Interventions
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Platelet rich plasma PRP
blood sample is collected to prepare platelet rich plasma injected in the canal
root canal treatment
conventional root canal treatment and obturation with guttapercha
Eligibility Criteria
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Inclusion Criteria
* Patients with necrotic pulp in mandibular molar permanent teeth with closed apex
Exclusion Criteria
* Patients with systemic diseases
* Pregnant women
* Patients that have allergy to ciprofloxacin or metronidazole
* Teeth that:
* Have vertical root fracture, coronal perforation, and calcification.
* re-treatment cases
* Non restorable
* Patients that have T.M.J. disorder
15 Years
35 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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yassmin Elsayed Ahmed
Assisstant lecturer-endodontic department
Locations
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Yassmin Elsayed Ahmed
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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yassmin ahmed
Role: primary
radwa emara
Role: backup
Other Identifiers
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CEBD-CU-2017-11-27
Identifier Type: -
Identifier Source: org_study_id