Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery
NCT ID: NCT04109417
Last Updated: 2019-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
15 participants
INTERVENTIONAL
2014-11-24
2017-10-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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osteotomy filled with PRP-gel and covered with PRP-biomembrane
the defect was filled with the previously activated autologous Platelet-rich plasma (PRP) gel and its supernatant. The site was then externally covered with the prepared bio-membrane composed of activated PRP which acted as an adjunct to the mucoperiosteal flap to stimulate tissue regeneration
osteotomy filled with PRP-gel and covered with PRP-biomembrane
osteotomy site left empty
osteotomy site following the surgical intervention was left empty
osteotomy site following the surgical intervention was left empty
Interventions
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osteotomy filled with PRP-gel and covered with PRP-biomembrane
osteotomy site following the surgical intervention was left empty
Eligibility Criteria
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Inclusion Criteria
2. Selected tooth with previous root canal therapy failure and in need of endodontic surgery.
3. Existence of a periapical radiographic lesion surrounding the root canal treated tooth, of size ≥ 1 cm.
4. Healthy periodontal condition (probing depth, mobility \& epithelial attachment level are all within normal range).
Exclusion Criteria
2. Periodontal ligament breakdown and presence of apicomarginal defects.
20 Years
45 Years
ALL
No
Sponsors
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Alexandria University
OTHER
Responsible Party
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salma genena
Lecturer of Endodontics, Conservative Dentistry Department
Principal Investigators
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salma genena, PhD
Role: PRINCIPAL_INVESTIGATOR
Alexandria University
Locations
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faculty of dentistry, Alexandria University
Alexandria, , Egypt
Countries
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Other Identifiers
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00010556
Identifier Type: -
Identifier Source: org_study_id