Evaluation of Post-operative Pain During Retreatment in Different Visits

NCT ID: NCT07014228

Last Updated: 2025-06-10

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 116 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-04-01
• Study Completion Date: 2023-07-01

Brief Summary

Endodontic retreatment is performed to alleviate symptoms of recurring infection, post-treatment disease after primary endodontic therapy. Retreatment can be performed in either single or multiple visits. and have their own implications. it is important to compare the patient response and post-op pain after single vs multi-visit reendo treatment.

Detailed Description

Introduction:

Treating endodontic failure cases has always been a challenge for the clinician due to the complex nature of disease which includes resistant microorganisms, iatrogenic errors and cleaning and shaping of un-instrumented areas. Endodontic retreatment can be done in either single or multiple visits. Multiple visits have the added advantage of placement of intracanal medicament resulting in decreased bacterial load and reduced pain, whereas single visit endodontic retreatment reduces chances of inter appointment microbial contamination. This study aims to evaluate post operative pain among both groups.

Objective:

To evaluate frequency of post-operative pain in endodontic retreatment cases after single vs multiple (two) visits root canal therapy.

Materials and Methods:

STUDY SETTING: Department of Operative Dentistry, AFID Rawalpindi.

Conditions

Post Operative Pain

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: TRIPLE

Study Groups

Single visit group

Endodontic retreatment in this group will be performed in a single visit. Initiated, deobturated, disinfection done and completed during the same visit.

Group Type: EXPERIMENTAL

single visit re-endo

Intervention Type: PROCEDURE

In this group, a single visit re-endodontic treatment will be performed and completed in the same visit, including all the steps.

Multi visit Group

Endodontic retreatment in this group will be performed in more than 1 visit. The retreatment will be initiated, deobturated, and disinfection done and completed in second or third visits..

Group Type: ACTIVE_COMPARATOR

multi visit re-endo

Intervention Type: PROCEDURE

In this group, a multi-visit re-endodontic treatment will be performed and completed over different visits, including all the steps.

Interventions

single visit re-endo

In this group, a single visit re-endodontic treatment will be performed and completed in the same visit, including all the steps.

Intervention Type: PROCEDURE

multi visit re-endo

In this group, a multi-visit re-endodontic treatment will be performed and completed over different visits, including all the steps.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Patients with unremarkable/ noncontributory medical history
• Age range between 15-45 years
• Cases of failed endodontic treatment resulting from inadequate root filling
• No systemic disease
• No periodontal disease

Exclusion Criteria

• Patients having teeth with periodontal pathology
• root fractures
• Immature root apices
• Endodontic posts
• Root perforations
• Immunocompromised health were excluded from the study.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Armed Forces Institute of Dentistry, Pakistan

OTHER

Sponsor Role: lead

Responsible Party

Ahmed Abdullah

Principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Armed Forces Institute of dentistry

Rawalpindi, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

Re-endo pain comparison

Identifier Type: -

Identifier Source: org_study_id